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General Rheumatology

News, opinions and meeting coverage in rheumatology.

A computer rendering of a transparent body with inflamed intestines highlighted.

TNF Blockers for IBD Tied to Risk for Immune-Mediated Diseases

"Paradoxical" finding puzzles researchers

A medical illustration of vagus nerve stimulation.

Those Studies Backing Vagus Nerve Stimulation for RA? Umm...

Randomized trial gives hopes for novel treatment a cold shower

A photo of an adult woman鈥檚 hands affected by rheumatoid arthritis

Biologics Keep Early RA in Check for at Least 1 Year

New data confirm earlier shorter-term findings

A CT scan of the spine of a senior male.

Imaging for Back and Joint Pain: Overuse Is an International Problem

Australian primary care docs love to order scans, just like their American counterparts

A photo of a bottle of Xeljanz over an x-ray image of a person鈥檚 hands gnarled by rheumatoid arthritis

Xeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests

Australian researchers perform "target trial emulation" to compare popular drugs

A computer rendering of intestinal microflora

Gut Microbiome Instability Associated With Lupus Nephritis Flares

One specific gut microbe may be a major factor

A photo of a box of Ofev (nintedanib) over a CT scan of interstitial lung disease.

Check SSc-ILD Patients on Ofev for Malnutrition, Study Suggests

Trial data show rates higher, though still low, with drug versus placebo

A photo of a mature male rheumatologist examining the x-rays of her female patient鈥檚 knees.

Do Rheumatologists See Past RA Patients' Race?

Randomized study finds no disparities in biologics prescribing, but questions linger

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Two-Drug Combo Wins for Refractory Gout

Phase III results back potential competitor for pegloticase-methotrexate treatment

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

First-in-Class Sjogren's Drug Passes Mid-Stage Test

Novel agent targets CD40 ligand

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Cardiovascular Risk Models Still Fall Short for Arthritis Patients

Of three major prognostic tools, none hit the mark

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

More Evidence Backs Gout Benefit for Gliflozin Agents

New study finds marked risk reduction tied to drugs' urate-lowering effect

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

More Success for CAR T-Cell Therapy in Rheumatic Disease

Stunning improvement for two patients with rare form of autoimmune myositis

A photo of bottles of varying doses of Jakafi.

JAK Inhibitor Shows Promise in Severe Type of Sclerosis

Study finds genetic basis long sought in disabling pansclerotic morphea, leading to effective tx

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Trial Shows RA Can Be Stopped at Preclinical Stage

Familiar biologic halts progression in high-risk patients with just a few painful joints

EULAR over a photo of MiCo Convention Center in Milan, Italy.

Benefits Found for Hand OA Drug Treatments

In separate studies, one old standby and one newer biologic appeared helpful

A photo of a senior woman massaging her aching jaw.

Here, Exactly, Is How Age of Onset Affects Giant Cell Arteritis

Disease characteristics, risk factors for complications differ between young and old

A photo of a wincing mature woman holding her sore neck and sitting in front of a laptop.

Oral Agent Cuts Fibromyalgia Pain in Trial, but ...

Publication comes after another study's failure to demonstrate benefit

Illustration of two legs and feet with ankle swelling

Make the Diagnosis: When an 'Innocuous' Ankle Injury Isn鈥檛

A 52-year-old woman presented to the doctor with left anterior ankle pain and foot swelling, decreased range of motion, and gait disturbance that had developed steadily over the past 4-6 weeks. Can you diagnose the patient?

A photo of human papillomaviruses in the bloodstream.

Mysterious White Blood Cell Disorder Not Just 'AIDS Without HIV'

Idiopathic CD4 lymphocytopenia not so heterogenous after all

A photo of a blood sample laying on genetic testing results.

B-Cell Stimulating Factors Tied to Lymphoma in Sjogren's

Findings may bolster interest in BTK inhibitors for autoimmune diseases

A photo of a man holding his trembling hand.

More Evidence Links Parkinson's With Autoimmune Disease

Exact mechanism remains speculative, however

A computer rendering of a man鈥檚 transparent head with the temporal artery highlighted.

Aging Mechanisms Tied to Giant Cell Arteritis

Small study may help explain how some GCA drugs actually work

The Drug Company That Prospered Without Creating Any Drugs

A look at Horizon Therapeutics' tactics

A computer rendering of the boxes and vials of Gamifant 10 mg and 50 mg.

Interferon Blocker Crushes Macrophage Activation Syndrome

Small trial shows promise for treating life-threatening complication of rheumatic diseases

A photo a man with atopic dermatitis on his forearms.

Asthma, Eczema Tied to Osteoarthritis Risk

Suggests OA is not just about wear and tear

A photo of a mature man opening a prescription medication bottle.

RA in Remission? Stopping DMARDs May Be OK

Provocative new data from ARCTIC REWIND

A photo of a male surgeon tying his mask on after scrubbing up.

Revolving Door in OR Makes Surgeries Less Efficient

Intraoperative staff swaps tied to longer operative time for hip, knee replacements

A photo of a bottle of Xeljanz tablets over a CT image of a patient with interstitial lung disease.

Tofacitinib May Reduce Risk of Interstitial Lung Disease in RA Patients

Retrospective study shows a 69% lower risk with tofacitinib compared with adalimumab

A photo of a person about to receive a hyaluronic acid injection in their knee.

Docs' Liking for Knee Injection Tied to Industry Payments

Threefold rate for giving hyaluronic acid shots among those paid more than $100

A photo of a bottle of Xeljanz tablets over a CT scan of pulmonary impairment from granulomatosis with polyangiitis

JAK Inhibitor Succeeds in Refractory Vasculitis

Seven of 11 patients respond after failing multiple previous meds

A photo of the vial and packaging of Saphnelo over a photo of a woman鈥檚 face with discoid lupus erythematosus

New Lupus Drug Cuts Skin Disease When Other Agents Fail

Small study backs anifrolumab for salvage therapy

A photo of a woman with knee joint effusion from psoriatic arthritis

Psoriatic Arthritis: Depressing News on Second- and Later-Line Treatments

Real-world data indicate most patients who fail a first biologic drug never obtain remission

A computer rendering of periodontal disease.

Study Suggests Path Connecting Periodontal Disease With Rheumatoid Arthritis

Exposing immune system to citrullinated bacterial proteins seen as trigger

A photo of a Taltz injection pen over MRI images of sacroiliac articulation

Taltz Safety, Efficacy Stay Robust in Spondyloarthritis at 3 Years

Benefits appear durable for patients in a long-term extension

A portrait of a senior woman with a butterfly rash on her cheeks.

Older Lupus Patients Need Follow-Up After Hospital Discharge ... or Else

Medicare data show what happens when it's neglected

A photo of an Opal inertial sensor.

Wearable Sensors Show Promise for Remote OA Assessment

Provide good data and most patients can manage them, small trial indicates

A computer rendering of antibodies causing inflammation in rheumatoid arthritis

Rheumatoid Factor and ACPA, Meet Potential New Partners for RA Diagnosis

Additional autoantibodies found to improve sensitivity in early-stage disease

A close up of a male nurse giving a male patient a covid vaccination

Study: Diminished COVID Vaccine Response in Lupus

Immunosuppressants seem responsible; mycophenolate "holiday" may help

A close up of a healthcare worker drawing blood from a man鈥檚 arm.

Blood Test Bests Standard OA Prognostic Models in Early Study

Multi-marker panel does a better job of predicting who will show rapid progression

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