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General Rheumatology

News, opinions and meeting coverage in rheumatology.

Overweight woman suffering from knee pain.

Surprising Link Between Weight Gain and RA Activity

Hint: it's not the worsening you probably expected

A photo of the prefilled syringe of Bimzelx over an MRI image of sacroiliac articulation in ankylosing spondyloarthritis

Bimekizumab Data in axSpA Look Good Through 1 Year

U.S. approval status for IL-17A/F inhibitor still in limbo

A photo of a Kevzara prefilled syringe.

Everything (Maybe) You Wanted to Know About Sarilumab for PMR

Published details may raise questions about FDA's approval

FDA APPROVED tocilizumab biosimilar (Tofidence) over an x-ray image of a child鈥檚 arthritic hands.

Actemra Biosimilar Approved

But Biogen product doesn't get all the original's indications

A close up photo of a vial of Haloperidol

Could This Neuroleptic Ward Off RA?

Retrospective data suggest a preventive effect for old-line antipsychotic drug

A photo of a female physiotherapist examining her male patient鈥檚 back in an examination room.

Here's Another Racial-Ethnic Disparity in Back Pain Care

Nonwhite patients who overuse opioids are given nonpharmacologic alternatives less often

A close up photo of a bottle of hydroxychloroquine tablets

Rheum Patients on HCQ: Stick With It or Face Heart Consequences

Population-based study links adherence with risk for cardiovascular events

A photo of a nurse collecting a blood sample from her female patient.

Run This Test Before Diagnosing Fibromyalgia

Study suggests 10% of cases may have easily treatable cause

A photo of the packaging and vial of Ilaris

What Changed FDA's Mind About Ilaris for Gout?

Approval comes after previous rejections

A close up photo of the scar on a woman鈥檚 knee from from knee replacement surgery

Joint Replacement Outcomes a Bit Better With Patient Reports Post-Surgery

Not a huge benefit, study finds, but could be a step toward more consistent follow-up care

A photo of two bottles of Eliquis tablets.

U.S. Unveils First 10 Drugs for Medicare Price Negotiations

Treatments for heart failure, Crohn's disease, and diabetes make the list

A photo of a man鈥檚 foot swollen and inflamed by gout.

Case Grows for SGLT2 Inhibitors as Gout Treatment

Large cohort study shows expansive benefits

A computer rendering of a macrophage releasing cytokines.

Blood Test Could Ease Diagnosis of Kids' Inflammatory Conditions

Just one biomarker distinguished Kawasaki disease from others with similar clinical features

A close up photo of a man self-injecting in his stomach fat.

Still No Easy Way to Take RA Patients Off Anti-TNF Drugs

Randomized trial tests a withdrawal strategy, with mixed results

A photo of a woman鈥檚 hand and arm affected by psoriatic arthritis.

Tool Predicts PsA Progression From Psoriasis, No Fancy Biomarkers Needed

New model estimates risk from routine clinical parameters

A CT scan of pulmonary fibrosis

Certain Medications Tied to Post-COVID Pulmonary Fibrosis

Rituximab and chemotherapy singled out in U.S. dataset

A photo of a box of prednisolone 5 mg tablets

Steroid Tapering Called Safe in Older RA Patients

Trial follow-up demonstrates feasibility, though not without some risk

A photo of a male business man tucking a wad of cash into the pocket of a male physician.

Rheumatology Journals Rife With Faulty Conflict-of-Interest Disclosures

Most authors receiving industry payments relevant to their research failed to report them

A transmission electron micrograph of rotavirus particles.

Rotavirus Hospitalization in Kids Linked to Autoimmune Disease Later On

Higher risks for arthritis, connective tissue disorders, other diseases seen in Korean study

A computer rendering of the intestinal microbiome

Gut Biome Altered in Inflammatory Arthritis, but Causal Direction Unclear

Authors of new study ready to exonerate intestinal flora as a cause of joint disease

A photo of a mature woman resting on her closed laptop at a table in her home.

Arthritis and Long COVID: A Double Whammy

Worse pain and less functional ability with lingering virus symptoms, patients say

A computer rendering of a transparent body with inflamed intestines highlighted.

TNF Blockers for IBD Tied to Risk for Immune-Mediated Diseases

"Paradoxical" finding puzzles researchers

A medical illustration of vagus nerve stimulation.

Those Studies Backing Vagus Nerve Stimulation for RA? Umm...

Randomized trial gives hopes for novel treatment a cold shower

A photo of an adult woman鈥檚 hands affected by rheumatoid arthritis

Biologics Keep Early RA in Check for at Least 1 Year

New data confirm earlier shorter-term findings

A CT scan of the spine of a senior male.

Imaging for Back and Joint Pain: Overuse Is an International Problem

Australian primary care docs love to order scans, just like their American counterparts

A photo of a bottle of Xeljanz over an x-ray image of a person鈥檚 hands gnarled by rheumatoid arthritis

Xeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests

Australian researchers perform "target trial emulation" to compare popular drugs

A computer rendering of intestinal microflora

Gut Microbiome Instability Associated With Lupus Nephritis Flares

One specific gut microbe may be a major factor

A photo of a box of Ofev (nintedanib) over a CT scan of interstitial lung disease.

Check SSc-ILD Patients on Ofev for Malnutrition, Study Suggests

Trial data show rates higher, though still low, with drug versus placebo

A photo of a mature male rheumatologist examining the x-rays of her female patient鈥檚 knees.

Do Rheumatologists See Past RA Patients' Race?

Randomized study finds no disparities in biologics prescribing, but questions linger

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Two-Drug Combo Wins for Refractory Gout

Phase III results back potential competitor for pegloticase-methotrexate treatment

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

First-in-Class Sjogren's Drug Passes Mid-Stage Test

Novel agent targets CD40 ligand

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Cardiovascular Risk Models Still Fall Short for Arthritis Patients

Of three major prognostic tools, none hit the mark

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

More Evidence Backs Gout Benefit for Gliflozin Agents

New study finds marked risk reduction tied to drugs' urate-lowering effect

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

More Success for CAR T-Cell Therapy in Rheumatic Disease

Stunning improvement for two patients with rare form of autoimmune myositis

A photo of bottles of varying doses of Jakafi.

JAK Inhibitor Shows Promise in Severe Type of Sclerosis

Study finds genetic basis long sought in disabling pansclerotic morphea, leading to effective tx

EULAR over a photo of the MiCo Convention Center in Milan, Italy.

Trial Shows RA Can Be Stopped at Preclinical Stage

Familiar biologic halts progression in high-risk patients with just a few painful joints

EULAR over a photo of MiCo Convention Center in Milan, Italy.

Benefits Found for Hand OA Drug Treatments

In separate studies, one old standby and one newer biologic appeared helpful

A photo of a senior woman massaging her aching jaw.

Here, Exactly, Is How Age of Onset Affects Giant Cell Arteritis

Disease characteristics, risk factors for complications differ between young and old

A photo of a wincing mature woman holding her sore neck and sitting in front of a laptop.

Oral Agent Cuts Fibromyalgia Pain in Trial, but ...

Publication comes after another study's failure to demonstrate benefit

Illustration of two legs and feet with ankle swelling

Make the Diagnosis: When an 'Innocuous' Ankle Injury Isn鈥檛

A 52-year-old woman presented to the doctor with left anterior ankle pain and foot swelling, decreased range of motion, and gait disturbance that had developed steadily over the past 4-6 weeks. Can you diagnose the patient?

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