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General Rheumatology

News, opinions and meeting coverage in rheumatology.

Superior migration of humeral head

Make the Diagnosis: There are Lots of Clues, but Can You Make the Diagnosis?

A 68-year-old man presented to the doctor with complaints of right shoulder pain, joint stiffness, and decreased range of motion that developed over the last 2 months. Can you diagnose the patient?

A photo of row houses in Philadelphia.

Poor Neighborhood, More Than Race, Predicts Greater Lupus Skin Severity

Blackness, per se, seen as less important than area socioeconomics

A computer rendering of a transparent body with the kidneys highlighted.

This Drug Class Keeps AA Amyloidosis in Check

Staves off end-stage renal disease, retrospective study indicates

A photo of smog over London.

Genes, Air Pollution Combine to Raise Lupus Risk

British data suggest how environmental and genetic factors add together

A distorted Amsler grid over a photo of an eye.

Rheumatology Meds Seen Cutting AMD Risk

Claims data point to possible protective effect for one common drug class

A photo of a mature woman鈥檚 knee x-ray on a monitor as she meets with a female rheumatologist in the background.

Osteoarthritis Diagnosis Portends Sickly Later Life

20-year study portrays OA as risk factor for multiple comorbidity

A computer rendering of periodontitis.

Wait, Maybe Periodontal Disease Doesn't Promote Rheumatoid Arthritis (or Vice Versa)

Danish study suggests surprising explanation for association

A photo of a woman wearing an apron carrying a frozen pizza on a baking sheet.

Do Ultraprocessed Foods Increase Lupus Risk for Women?

Sobering findings from Nurses' Health Study

A photo of a man鈥檚 hand inflamed by systemic lupus erythematosus

Could Two Targeted Therapies Be Better Than One in Lupus?

Mid-stage trial tests a JAK inhibitor as monotherapy and in combination with a BTK blocker

A close up photo of broccoli soup.

Really, Soup Might Help in Osteoarthritis?

Not just any soup. And no chicken needed.

A photo of a prescription bottle of metformin tablets next to a glucose monitor.

Lupus Complications Reduced With Common Diabetes Drug

Metformin benefits seen extending way beyond its glucose-lowering properties

A computer rendering of test tubes of blood lying on a test form.

Use This Common Cardiac Test in RA Patients, Study Suggests

Identifies heart risks not captured by conventional risk factors

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

SpA Patients Do Just Fine Managing Their Own Follow-Up Care

Randomized trial suggests usual practice is wasteful

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Izokibep Marches on for Psoriatic Arthritis

Early phase III data cement case for novel IL-17A inhibitor

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Novel URAT1 Inhibitors Advance for Gout

New treatment options on the horizon come into better focus

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

OA Patients Get Long-Term Benefit From Lifestyle Improvements

Improvement in pain and function lasted well after formal program ended

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Is 'Difficult-to-Treat' RA a Lost Cause?

The name says it all, but progress appears to be coming

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

CAR-T Treatment Continues to Astonish in Rheumatologic Diseases

Numbers of patients, length of follow-up keep growing with no visible downside (yet)

A close up photo of a Humira prefilled syringe.

Humira Clobbers Biosimilars in Battle for Part D Coverage

Pricing, payer policies keep market leader on top

A photo of a bottle of Olumiant tablets.

JAK or TNF Inhibitor as First Targeted Drug for Rheumatoid Arthritis?

Pragmatic head-to-head study finds a winner, with caveats

A photo of a senior woman grimacing while clutching her painful wrist.

In RA, Poorly Controlled Pain Portends Even More Serious Problems

Australian study documents risks for life-threatening complications

A scanning electron microscope image of T cells.

Finally, a Treatment Emerges for Autoimmune Polyendocrine Syndrome

And it's on the pharmacy shelf now

A photo of a bottle of Olumiant tablets.

Not All COVID Patients Benefit From JAK Inhibitor

Post-hoc analysis shows that body weight makes an important difference

A photo of a senior man lying in a hospital bed and reading on a tablet.

Study Confirms: No Great Options for Treating VEXAS

Efficacy versus safety is the inevitable tradeoff, and efficacy isn't that good to begin with

A photo of Antarctic krill.

Krill Oil Fails in New Osteoarthritis Trial

Now the question is how to reconcile this study with others finding a benefit

A computer rendering of antibodies in the blood.

Doubt Cast on MGUS-Autoimmune Disease Link

Population-based study fails to confirm earlier findings

A photo of a foot swollen from gout.

Yet Another Benefit for Metformin?

Study suggests a surprising effect in rheumatologic disease risk

A photo of the tablet, container, and packaging of Rinvoq.

One-Year Data Back Upadacitinib for Clinical Spondyloarthritis

Adds to 14-week results that powered FDA approval for non-radiographic axial spondyloarthritis

A photo of a man receiving a knee injection by a male physician.

Stem Cell Injections in Mexico Led to Drug-Resistant Infections

Three patients acquired Mycobacterium abscessus infections after medical travel

A photo of a bottle of hydroxychloroquine tablets.

Retinopathy With Long-Term HCQ Use: Large Study IDs Risk Factors

Hint: it's not just the cumulative dose

A photo of a mother checking her daughter鈥檚 temperature.

How Does FMF Affect Adolescent Females? Study Offers New Details

And proposes a treatment algorithm to manage the disease in this population

A photo of a female radiologist performing temporal ultrasound of her senior male patient

Imaging-Only Diagnosis of Giant Cell Arteritis Is Feasible

Color Doppler ultrasound proves mettle as standalone method

A computer rendering of pliers extracting a tooth from a lower jaw.

Missing Teeth and Joint Pain? RA May Be Imminent

You may not even have to ask if patient has had periodontal disease

A photo of runners in the Brooklyn half and full Marathon in New York City.

Study: Skinny-Leg Runners Face Higher Rates of Knee Arthritis

Questions about risks from weight-bearing activities may now be settled

A close up photo of the hand of a person with systemic lupus erythematosus

Can Innate Immune System Be Targeted Directly in Lupus?

Japanese researchers open new front in SLE therapy

A photo of a mature man massaging his knee.

Hands-On Treatment May Help in Knee Osteoarthritis

And patients can administer it themselves

A photo of Kristin Fritz

'I Feel So Violated': Over 200 Patients Accuse Doc of Sex Abuse, Unnecessary Exams

Alleged victims included women and several men

A photo of a young male fitness trainer guiding his senior female client through a step exercise.

Here's a Good Exercise Option for Hip OA

Program emphasizing balance and stability equals strength-directed training

A photo of a senior rheumatologist discussing hand x-rays with his female patient

Study: Treat-to-Target Success in Early RA Is Durable

Good outcomes generally maintained for up to two decades

A photo of a female physician performing an ultrasound of the knee of a young girl

No Response to TNF Inhibitor in JIA? Another May Do the Trick

Registry study finds no advantage for switching to a different drug class

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