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General Rheumatology

News, opinions and meeting coverage in rheumatology.

A photo of a bottle of Olumiant tablets.

JAK or TNF Inhibitor as First Targeted Drug for Rheumatoid Arthritis?

Pragmatic head-to-head study finds a winner, with caveats

A photo of a senior woman grimacing while clutching her painful wrist.

In RA, Poorly Controlled Pain Portends Even More Serious Problems

Australian study documents risks for life-threatening complications

A scanning electron microscope image of T cells.

Finally, a Treatment Emerges for Autoimmune Polyendocrine Syndrome

And it's on the pharmacy shelf now

A photo of a bottle of Olumiant tablets.

Not All COVID Patients Benefit From JAK Inhibitor

Post-hoc analysis shows that body weight makes an important difference

A photo of a senior man lying in a hospital bed and reading on a tablet.

Study Confirms: No Great Options for Treating VEXAS

Efficacy versus safety is the inevitable tradeoff, and efficacy isn't that good to begin with

A photo of Antarctic krill.

Krill Oil Fails in New Osteoarthritis Trial

Now the question is how to reconcile this study with others finding a benefit

A computer rendering of antibodies in the blood.

Doubt Cast on MGUS-Autoimmune Disease Link

Population-based study fails to confirm earlier findings

A photo of a foot swollen from gout.

Yet Another Benefit for Metformin?

Study suggests a surprising effect in rheumatologic disease risk

A photo of the tablet, container, and packaging of Rinvoq.

One-Year Data Back Upadacitinib for Clinical Spondyloarthritis

Adds to 14-week results that powered FDA approval for non-radiographic axial spondyloarthritis

A photo of a man receiving a knee injection by a male physician.

Stem Cell Injections in Mexico Led to Drug-Resistant Infections

Three patients acquired Mycobacterium abscessus infections after medical travel

A photo of a bottle of hydroxychloroquine tablets.

Retinopathy With Long-Term HCQ Use: Large Study IDs Risk Factors

Hint: it's not just the cumulative dose

A photo of a mother checking her daughter鈥檚 temperature.

How Does FMF Affect Adolescent Females? Study Offers New Details

And proposes a treatment algorithm to manage the disease in this population

A photo of a female radiologist performing temporal ultrasound of her senior male patient

Imaging-Only Diagnosis of Giant Cell Arteritis Is Feasible

Color Doppler ultrasound proves mettle as standalone method

A computer rendering of pliers extracting a tooth from a lower jaw.

Missing Teeth and Joint Pain? RA May Be Imminent

You may not even have to ask if patient has had periodontal disease

A photo of runners in the Brooklyn half and full Marathon in New York City.

Study: Skinny-Leg Runners Face Higher Rates of Knee Arthritis

Questions about risks from weight-bearing activities may now be settled

A close up photo of the hand of a person with systemic lupus erythematosus

Can Innate Immune System Be Targeted Directly in Lupus?

Japanese researchers open new front in SLE therapy

A photo of a mature man massaging his knee.

Hands-On Treatment May Help in Knee Osteoarthritis

And patients can administer it themselves

A photo of Kristin Fritz

'I Feel So Violated': Over 200 Patients Accuse Doc of Sex Abuse, Unnecessary Exams

Alleged victims included women and several men

A photo of a young male fitness trainer guiding his senior female client through a step exercise.

Here's a Good Exercise Option for Hip OA

Program emphasizing balance and stability equals strength-directed training

A photo of a senior rheumatologist discussing hand x-rays with his female patient

Study: Treat-to-Target Success in Early RA Is Durable

Good outcomes generally maintained for up to two decades

A photo of a female physician performing an ultrasound of the knee of a young girl

No Response to TNF Inhibitor in JIA? Another May Do the Trick

Registry study finds no advantage for switching to a different drug class

A photo of a technician holding a tray of vials of stem cells frozen in liquid nitrogen

Standard Drug Tx as Good as Stem Cell Transplant for Scleroderma?

Surprising finding from comparative study

A photo of a vial of Comirnaty monovalent XBB.1.5 COVID-19 vaccine and several single-use syringes.

CDC: Latest COVID Vax Cuts Hospitalization Risk in Immunocompromised People

But fewer than one in five of this vulnerable group have received the updated shot

A close up photo of a box of tissues

Predicting Vasculitis Relapse? It's SNOT That Hard

Sino-nasal symptoms markedly raise the risk, study suggests

A computer rendering of antibodies and red and white blood cells.

Can an Autoimmunity Lead to Immune Deficiency?

Studies may explain some cases of rare opportunistic infections

A photo of psoriasis on a man鈥檚 knees.

Psoriatic Arthritis: Updated Guideline Clarifies Treatment Sequence

EULAR provides easy-to-understand algorithm

A photo of a senior woman receiving a covid vaccination from a female nurse.

How Often Should Immunocompromised People Get a COVID Booster?

Experts say about every 6 months, but that should be individualized

A computer rendering of Coccidioidomycosis fungus

Valley Fever Screens Found Lagging for Rheum Patients in Endemic Areas

A significant issue for DMARD and steroid users in the American Southwest

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Rheumatologist Found Dead; How COVID Changed Lives; Olivia Munn's Breast Cancer

Health news and commentary from around the Web gathered by 51成人动漫 staff

A close up photo of a senior woman holding a glass of water and a white pill.

Seniors, Doctors at Odds on Opioid Risks and 'Deprescribing'

Conversations between primary care physicians and older patients often "challenging"

A computer rendering of COVID viruses infecting a cell.

COVID-19 Tied to Increased Risk for Rheumatic Disease

Maybe not a form of long COVID, but a concern just the same

Putting Together the Puzzle Pieces of Self-Compassion

"We're all yearning to be seen, to be heard, and to be believed"

A photo of a male physician inspecting his senior female patient鈥檚 knee replacement scars.

Multimodal Pre-Op Program Aids Knee Replacement Candidates

Patients feel better as they wait for surgery; a few find they no longer need it

A photo of a man sitting on a couch, holding a tissue, and pressing his hand to his nose.

Sinusitis Tied to Later Autoimmune Disease

Olmsted County analysis points to substantial risk

A photo of a woman self-injecting with an Orencia auto injector

Another Study Backs Treatment for Preclinical Rheumatoid Arthritis

Progression to full-blown RA slowed

New Treatment for NASH; Human Milk for Preterm Infants

Also in TTHealthWatch: managing gout with uric acid levels

A screenshot of the pharmaceutical CEOs facing the hearing.

Senators Thrash Pharma CEOs for Pricing Drugs Higher in the U.S.

Sen. Bernie Sanders blamed "corrupt" system, well-paid lobbyists

A computer rendering of an antibody and strands of RNA

Novel Lupus Approach Yields Mixed Results in Early Trial

Hints of benefit seen in patients with more active disease

A microscope image of uric acid crystals

Early Marker Found for Long-Term Gout Flare Potential

And the bad news: urate-lowering therapy seemed to make no difference

A computer rendering of X and Y chromosomes.

A Clue on Why Lupus, Other Autoimmune Diseases Strike Far More Women Than Men

New research shows that the extra X chromosome is involved, but in an unexpected way

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