Huntington's Disease Updates
Juvenile-Onset Huntington’s Disease: A More Nuanced Approach to Monitoring Progression
This study identified specific motor skills as highly sensitive markers of juvenile-onset Huntington’s disease (JOHD) progression, offering more precise tools for tracking the disease and designing future treatments tailored to patients with JOHD.
In Huntington’s Disease, Exploring the Roles of Race, Ethnicity, and Education
A study identified racial and ethnic disparities in Huntington’s disease, as well as differences based on levels of education of patients, finding that minority patients may be disproportionately affected.
Neurogenetic Disease Patients and Caregivers May Benefit from End-of-Life Conversations
A French study based on questionnaires and interviews showed a willingness among patients with neurogenetic diseases and their primary caregivers to talk about sensitive issues like advance directives and end-of-life care.
In Huntington’s Disease, Depression is Different
Investigators call for psychosocial interventions in those with or at risk for Huntington’s disease. Taking a personalized approach to address factors such as concern for the future and sleep disturbances is essential.
In Early-Stage Huntington’s Disease, Cognitive Trajectories Vary
In a study of adults with early or early-mid Huntington’s disease, two types of patients emerged: those with a mild, slow progression of cognitive decline and those marked by a more rapid and aggressive decline. How did these groups compare with healthy controls?
Are Movement Disorders to Blame for a Lack of Social Awareness?
An examination of 50 relevant studies found that individuals with any of four major types of hyperkinetic movement disorders consistently exhibited impaired social cognition. What does this mean for them—and the professionals who care for them?
Huntington’s Disease: A Look at the Global Pace
This updated systematic review and meta-analysis—the first in at least a decade—analyzed rates of this rare inherited neurological disorder in 21 countries, across multiple continents. Have rates gone up, down, or stayed the same?
In Huntington’s Disease, How Sleep and Circadian Patterns Affect Cognition
In patients with Huntington’s disease, poorer sleep is associated with poorer cognitive function. But would these patients benefit from targeted sleep and circadian rhythm modification to improve cognitive function?