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News, opinions and meeting coverage in primary care.

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Prion Disease on the Rise in the U.S.

Now the question is, why?

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Could Undiagnosed Neuro Condition Explain Grandpa's Falls?

Peripheral neuropathy found in many patients who weren't aware of it

FDA APPROVED testosterone undecanoate (TLANDO) over a man holding a white pill between his fingers and a glass of water.

Another Oral Testosterone Undecanoate OK'd for Hypogonadism

FDA approval of Tlando follows in the footsteps of Jatenzo

A photo of the vials and packaging of Iron Dextran Injection, USP

Pumping (IV) Iron Linked to Varying Anaphylaxis Risk for Older Adults

Study finds risk was low, but unequal across different products

A photo of a senior woman in a wheelchair holding her knee; both knees have scars from knee replacement surgery.

'It's an Alien Knee in There': Mixed Feelings After Joint Replacement

Study highlights common, but rarely discussed, problem

A photo of the vial and packaging of Aduhelm.

Aducanumab Data Finally Published, but Alzheimer's Experts Spot Problems

Questions raised about secondary endpoints

An ophthalmologist measures the intraocular pressure of a patient鈥檚 eye using a tonometer.

Glaucoma: The Newest Autoimmune Disease?

Researchers argue for a "paradigm shift"

A computer rendering of a syringe and the the knee joint of a skeleton.

Reassurance on Steroid Shots for Knee OA

Study counters fears that injections worsen underlying pathology

A senior woman sitting in bed massages her toes.

Peripheral Nerve Problems Tied to Later Dementia

Findings may indicate shared susceptibility to neurodegeneration

Medical staff members from Jiangsu Province work at an ICU ward of the First Hospital of Wuhan City in Wuhan, central China

Cognitive Effects Persist in Older COVID Patients

Long-term cognitive decline common after SARS-CoV-2 hospitalization

An x-ray image of knees affected by osteoarthritis.

Hopes Dashed for Novel Osteoarthritis Treatment

Noninvasive therapy looked like a sure winner until trial results came in

A portrait of a mature man cupping his ear with his hand in an effort to hear.

Hearing Loss, Epilepsy May Be Early Signs of Parkinson's Disease

Known symptoms like tremor spotted in primary care records 10 years before diagnosis

A photo of a prescription bottle on its side spilling out white pills next to a blood pressure monitor.

ARB-Cancer Link May Come Down to Cumulative Exposure

Does a new paper resolve the conflicting safety data on the popular antihypertensives?

A photo of a senior woman in a wheelchair in a nursing home hallway.

Biden Administration Announces Steps to Improve Nursing Home Care

Measures include those aimed at increasing staffing and cutting down on unnecessary treatment

A photo of an effervescent tablet in water releasing bubbles.

Salt in Fizzy Tablets Linked to Heart, Death Risk

Warning signals seen for fast-acting acetaminophen and other drugs

A portrait of a mature bearded man with a tabby cat draped over his shoulder.

Owning a Pet May Protect Cognitive Health

Strongest benefit seen for long-term pet owners

A close up of a woman鈥檚 hand on an automatic blood pressure monitor

Non-Validated BP Monitors Are a Global Problem

Thousands of device models don't meet international standards

A senior man sits in a chair next to his bed and looks out the window.

Loneliness May Triple Dementia Risk

Even without dementia, lonely feelings linked with brain changes

A close up of a senior grandmother grasping her granddaughters hands

Mystery: Why Would Hand OA Be Less Severe in Black People?

Data contrast with previous findings for hip and knee osteoarthritis

STS over a photo of a surgeon performing a thoracic operation using a fiber optic head-light.

More Evidence for Prehab Before Cardiac Surgery

One center's initial experience suggests good perioperative results

A blue rubber gloved hand holds a test tube of blood in front of a brain MRI

Blood Biomarkers May Distinguish Dementia Disorders

Plasma levels show diagnostic, prognostic performance in varying dementia types

A blood pressure cuff, a stethoscope and a spilled prescription bottle of green pills.

Mixing and Matching BP Meds? Consider the Implications for Dementia

SPRINT analysis favors certain classes of antihypertensives

Strawberries, blueberries, grapes, red wine corks, and a bottle of balsamic vinegar

More Flavonoids, Better Parkinson's Outcome

Flavan-3-ols and anthocyanins consistently linked to lower mortality

A box of BinaxNOW rapid tests next to other products in a medicine cabinet in a home.

Medicare Patients Can't Get Their At-Home COVID Test Kits Covered -- Yet

But CMS says it's working to provide that coverage

The packaging and blister pack of Cymbalta

Muddled Picture for Antidepressant as Osteoarthritis Pain Reliever

Trial in primary care setting fails to confirm benefit seen in specialty clinics

An illustration depicting Alzheimer鈥檚 disease with amyloid plaques forming between neurons

Alzheimer's Drugs Race to FDA

After aducanumab, drug companies pivot to use the accelerated approval pathway

A Black woman monitors her continuous glucose monitor via her smartphone.

Wide Racial Gap for Diabetes Tech Use Among Medicare Patients

Insulin pump and CGM use significantly lower among black patients

A computer rendering of electricity crackling in a person鈥檚 head.

Post-Stroke Epilepsy Treatment May Influence Mortality

All-cause death lowest in people taking lamotrigine

A photo of Viagra pills blister pack and packaging.

Can Viagra Prevent Alzheimer's?

Sildenafil shows potential for drug repurposing

An illustration of a heartbeat over a silhouette of a senior woman.

Dementia Tied to Resting Heart Rate

Findings persist even after accounting for cardiovascular disease

A vial of Rituxan (rituximab) and bottle of Imbruvica (ibrutinib) capsules over a microscopy of mantle cell lymphoma.

Chemo-Free Regimen Highly Active in Older Mantle Cell Lymphoma Patients

Overall response rate of 96% with ibrutinib-rituximab, but cardiotoxicity a possible issue

A white rubber gloved hand injects platelet-rich plasma into a person鈥檚 knee

Another Trial, Another PRP Flop in Osteoarthritis

Fails to outperform saline in randomized trial

A computer rendering of bone affected by osteoporosis.

Bisphosphonate Therapy and Fracture Prevention: How Long Does It Take?

Meta-analysis determined minimum treatment time needed to see gains

The vial and packaging of Aduhelm (aducanumab) over a close up of a man鈥檚 hand with IV attached.

Let Ethics Guide Aducanumab Prescribing, AAN Says

Don't rely on FDA approval alone to make best choices for Alzheimer's patients

AAO over a photo of the Ernest N. Morial Convention Center in New Orleans, LA.

Microstent for Cataract Surgery Reduced Need for Glaucoma Meds

Device lowers eye pressure by promoting fluid flow through Schlemm's canal

AASLD over a computer rendering of the structure of the liver.

Need for Liver Transplants Rising Sharply in Seniors

Post-transplant mortality still higher versus younger patients, but improving over time

A medical illustration of a dopaminergic neuron in parkinson鈥檚 disease.

Early Parkinson's Treatment: AAN Issues New Guidelines

Levodopa usually is best first therapy for motor symptoms, neurology group says

An MRI image of a brain with Alzheimer鈥檚 disease.

One Aducanumab Patient, Six Brain Edema Episodes

"Uniquely complicated course" for patient treated with new Alzheimer's drug

A close up of a woman鈥檚 hands lifting a vial of Shingrix from a box.

Guillain-Barre Risk Up Slightly After Shingrix

Findings support FDA warning for recombinant zoster vaccine

A computer rendering of ankle osteoarthritis

No Love for PRP in Ankle Osteoarthritis Trial

Dutch researchers throw cold water on popular therapy

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