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Rheumatology

News, opinions and meeting coverage in rheumatology.

A senior woman sitting on her couch looks at her hands clenched into fists.

In RA, Little Risk for Recurrent Cancer With Biologic Treatment

Results important because most trials excluded patients with previous cancer, researchers note

Four statin tablets outside of a blister pack

Statins Not Linked With Rheumatoid Arthritis, Large Study Finds

Risks attenuated after adjustment for lipid levels

A young boy curled up on the sofa with stomach pain.

IBD and Pediatric Arthritis: Exploring the Link

Risk factors include enthesitis, family history, and etanercept use

A micrograph of pneumocystis (carinii) jiroveci

Pneumocystis Often Lethal in Dermatomyositis

Incidence of pneumonia high in MDA5-antibody-positive patients

A computer rendering of a lymph node cross section

Lymphoma in RA: Disease Activity Matters

Strongest risk factors were baseline disease activity scores and bone erosions

An image of of package of Xeljanz

FDA Slaps Restrictions on JAK Inhibitors Over Serious Safety Risks

Use for inflammatory conditions limited to those who fail on TNF blockers

Woman suffering from fibromyalgia neck pain.

Fibromyalgia: A New Feature of Long COVID?

Almost one-third of patients in Italian study had musculoskeletal sequelae

Photo of 72-year-old woman being evaluated for mild pain and joint stiffness in her hand.

What's Causing Cancer Patient's Joint Pain While on Checkpoint Inhibitor?

Here is how clinicians diagnosed this rare inflammatory side effect

A woman kisses her elderly mother on the forehead in the kitchen.

What Factors Predict RA in First-Degree Relatives?

Study may offer insight into preclinical phase to identify factors that predict progression

A bottle and tablet of Rinvoq (Upadacitinib) over a close up of a man scratching the eczema on the back of his hand

JAK Inhibitor Tops Mab for Eczema

New disease-modifying treatment option on the horizon

An overweight woman runs up concrete stairs in a park.

Healthy Lifestyle Limits Lupus Risk

Diet, exercise, weight, smoking, and moderate alcohol use contributed to lower risk in women

A mature man laying on a couch winces from abdominal pain.

New-Onset IBD and IL-17 Inhibitors: What Is the Risk?

Underlying inflammatory disease severity should be taken into account

FDA APPROVED immunoglobulins (IVIG; Octagam 10%) over photos of adults with dermatomyositis

FDA Approves IVIG for Dermatomyositis

Octagam 10% lands indication for adults following results of ProDERM trial

A doctor wearing blue rubber gloves holds the hand of a patient with psoriatic arthritis.

CV Risk in PsA: Do Drugs Matter?

Study weighs in on heart safety of TNF inhibitors versus other biologics

An empty prescription bottle laying on its side.

Slow Steroid Tapering Succeeds in SLE

Flare rates were significantly lower with gradual withdrawal than with low-dose maintenance

An x-ray image of erosive osteoarthritis of the hands.

Effective Treatments for Hand Osteoarthritis: The Search Goes On

Hydroxychloroquine not effective as disease-modifying drug for erosive hand OA, trial confirmed

A close up of a Heartmate 3 left ventricular assist device

Skin Rash Should Be a Huge Red Flag for LVAD Recipients, Group Says

New phenomenon suggests perils of not performing biopsy in time

A bottle and tablet of Rinvoq (upadacitinib) over an x-ray image of a spine with ankylosing spondylitis

Rinvoq Shows Promise in Spine Disease

1-year results in ankylosing spondylitis demonstrate efficacy for JAK inhibitor upadacitinib

Sagittal magnetic resonance images of psoriatic arthritis in the ankle region above a Stelara (ustekinumab) needle.

Target TNF or IL-12/23 in Psoriatic Arthritis?

Both TNF inhibitors and ustekinumab were effective in real-world use

A close up of a vial of methotrexate and a syringe in a man's hand

New ACR Rheumatoid Arthritis Guideline: Emphasis on Methotrexate

Many RA patients succeed with optimized use of the DMARD before adding another medication

A senior woman massages her painful arthritic hand

Pain Persists in RA, Even Without Inflammation

At 5 years, one-third of patients with rheumatoid arthritis still had "unacceptable" pain

A senior Asian woman sits on her couch experiencing knee pain.

Osteoarthritis: A Link With Parkinson's?

Inflammation may contribute to both joint and nerve degeneration

EULAR over a computer rendering of human body parts with the major joints glowing red

Secukinumab Shows Promise for Kids With Arthritis

More than 90% responded at week 12, study showed

EULAR over a computer rendering of human body parts with the major joints glowing red

Personalized Algorithm Helps Guide Rituximab Retreatment

For ANCA-associated vasculitis, fixed retreatment not needed if naive B cells reappear

EULAR over a computer rendering of human body parts with the major joints glowing red

IVIG a Winner for Dermatomyositis

Pivotal phase III trial shows clear efficacy

EULAR over a computer rendering of human body parts with the major joints glowing red

Nintedanib Slows Decline in RA-Associated Interstitial Lung Disease

Similar results to original larger trial seen in post-hoc analysis

EULAR over a computer rendering of human body parts with the major joints glowing red

Oral JAK 1 Inhibitor Eases Spine Inflammation in Ankylosing Spondylitis

Treatment with filgotinib resulted in significant improvements compared with placebo

EULAR over a computer rendering of human body parts with the major joints glowing red

Even Exposure to Passive Smoking Increases Risk of RA

Disease onset was earlier in women exposed to smoky rooms during childhood

EULAR over a computer rendering of human body parts with the major joints glowing red

Rituximab a Hazard in RA Patients With COVID

Poor outcomes were fourfold higher among rituximab users than for those on TNF inhibitors

A photo of a vial of Methotrexate for injection next to a syringe

Methotrexate Impairs COVID Vax Response

Can extra vaccine doses or discontinuing drug benefit patients with immune-mediated diseases?

A man's hand with psoriatic arthritis over a box of Ilumya (tildrakizumab-asmn) for injection.

Plaque Psoriasis Drug Shows Promise for Psoriatic Arthritis

Monoclonal antibody targets the IL-23 p19 subunit

A Stelara auto injector needle over a grid of close up psoriasis images.

For Safety, One Biologic a Winner in Psoriasis, Psoriatic Arthritis

Lower hospitalization rates compared with other biologics or small molecule therapies

'Talents' Land U.S. Researcher in Prison

Ohio MD pleaded guilty to lying on grant applications, planned to share research with China

A Taltz (ixekizumab) auto injector pen over a photo of a mans back, his spine highlighted in red

Stopping IL-17 Drug for Axial Spondyloarthritis? Expect Spinal Flares

But low disease activity regained if treatment restarted

A close up of a fresh modern surgical suture.

Op-Ed: Why the COVID Vaccine Didn't Work for Me

Millions of transplant patients need to be informed that they may not get sufficient protection

An illustration of a brain filled with lightbulbs, one is burning brightly, the others are dark.

The Death of One Little Girl Helped Millions

A case more than 35 years ago has spurred discoveries ever since

FDA ADCOMM oral avacopan over a medical illustration of vasculitis over a photo of a persons skin with purpura from vasculiti

FDA Panel to Weigh Avacopan's Fate for ANCA Vasculitis

Agency staff called out "interpretability" of phase III trial results ahead of Thursday's meeting

A photo of Carrie Ann Inaba

'Dancing With the Stars' Judge Carrie Ann Inaba's Autoimmune Diseases

TV host takes leave of absence

Bags of fentanyl tablets seized by the Drug Enforcement Agency

ED Docs Split Over Fentanyl Analogue Schedule 1 Extension

Will it save lives or prevent drug users from seeking help?

An artist rendition of fecal microbiota capsules

Results Disappoint for Fecal Transplant in Arthritis

But interest persists in targeting the gut-joint axis in psoriatic arthritis

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