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General Rheumatology

News, opinions and meeting coverage in rheumatology.

A photo of a senior woman in a wheelchair holding her knee; both knees have scars from knee replacement surgery.

'It's an Alien Knee in There': Mixed Feelings After Joint Replacement

Study highlights common, but rarely discussed, problem

An ophthalmologist measures the intraocular pressure of a patient鈥檚 eye using a tonometer.

Glaucoma: The Newest Autoimmune Disease?

Researchers argue for a "paradigm shift"

A computer rendering of a syringe and the the knee joint of a skeleton.

Reassurance on Steroid Shots for Knee OA

Study counters fears that injections worsen underlying pathology

A white pill laying in the hand of a person affected by systemic lupus erythematosus

Mixed Results for Oral Lupus Drug in Phase II

Mid-stage study offers hope but also reason for caution

A computer rendering of the pelvis with the spine and sacroiliac joints highlighted in red.

Ankylosing Spondylitis: Another Step Toward Individualized Therapy

Study IDs factors predicting response to TNF inhibitors

An x-ray image of knees affected by osteoarthritis.

Hopes Dashed for Novel Osteoarthritis Treatment

Noninvasive therapy looked like a sure winner until trial results came in

An overweight woman pours a meal replacement shake in to a glass in her kitchen

Fibromyalgia Patients See Rapid Benefit From Low-Cal Diet

With marked symptom reduction in just 3 weeks, weight loss not a factor

A teen girl lies on her side on a couch doubled up with a pained expression.

Kids With IBD Need Close Monitoring as They Grow Up

Meta-analysis confirms: substantially increased cancer risk in adulthood

A cartoon illustration of the figure: $269/hr pointing to a female doctor and $89/hr pointing to a sad male physician.

10 51成人动漫 With the Lowest Hourly Rate

Calculated by annual salary divided by number of hours worked

A photo of a woman lying in an MRI scanner.

Dyspnea in Woman With RA Reveals a Diaphragmatic Lipoma

MRI can help differentiate these benign soft-tissue masses from more aggressive liposarcomas

A computer rendering of antibodies in the bloodstream.

Predicting Treatment Response in Inflammatory Muscle Disorders

Swedish registry study elicits factors associated with improvement

A photo of a man鈥檚 hand with psoriatic arthritis over the packaging of Tremfya

Two Years On, Tremfya Still Shines in Psoriatic Arthritis

Efficacy increases in long-term extension data

A close up of a senior grandmother grasping her granddaughters hands

Mystery: Why Would Hand OA Be Less Severe in Black People?

Data contrast with previous findings for hip and knee osteoarthritis

A bottle of Xeljanz tablets over yellow caution tape forming an X

Trial Data Confirm Heightened Risks With JAK Inhibitor

May help patients and clinicians better weigh benefit against adverse effects

A close up of a senior woman鈥檚 arthritic hand resting on a cane.

How Preventable Is Rheumatoid Arthritis?

Big study sets a number

A close up of a woman pushing a statin pill out of a blisterpack

Psoriasis Patients, Docs Want to Do More to Prevent Heart Problems

Despite well-known cardiovascular risks, most patients currently undertreated

A photo of vasculitis rash on a woman鈥檚 legs

Don't Expect Much From COVID Vax in This Patient Group

With rituximab on board, even third doses didn't induce meaningful antibody response

The packaging and blister pack of Cymbalta

Muddled Picture for Antidepressant as Osteoarthritis Pain Reliever

Trial in primary care setting fails to confirm benefit seen in specialty clinics

A box of Cosentyx 150 mg solution for injection in two pre-filled pens

Biologic Disappoints for Arthritis Achilles' Inflammation

But phase III trial did find some patient-oriented benefits

ACR over a photo of the Moscone Center in San Francisco, CA.

For Systemic JIA, Start Biologics Early

Observational study shows excellent efficacy in systemic pediatric arthritis

ACAAI over a photo of the Ernest N. Morial Convention Center in New Orleans, LA.

HAE Still Drawing Attention From Drugmakers

Two new products show midstage promise in hereditary angioedema

ACR over a photo of the Moscone Center in San Francisco, CA.

Secukinumab: An Up-and-Coming Option in Giant Cell Arteritis?

Phase II trial found sustained remission with steroid-sparing effects

ASN over a computer rendering of a transparent torso with the kidneys highlighted in black.

Avacopan Helps Vasculitis Patients With Renal Impairment Wean Off Steroids

Patients saw better eGFR recovery compared with prednisone

ACR over a photo of the Moscone Center in San Francisco, CA.

Vitamin D and Disease Prevention: Worth Another Look?

Incidence of autoimmune disease decreased by 25-30% with dietary supplements

ACR over a photo of the Moscone Center in San Francisco, CA.

Guselkumab Response Durable in Psoriatic Arthritis

Skin and joint improvements persisted through 2 years of follow-up

ACAAI over a photo of the Ernest N. Morial Convention Center in New Orleans, LA.

Could This Biologic Drug Work in Patients Lacking Its Target?

Bizarre finding with omalizumab

A computer rendering of two monoclonal antibodies of differing coloration over an inflamed bronchial tube.

Mixed Results With Anti-Interleukin Biologics in Asthma

One shows promise; another fails miserably (and mysteriously)

A computer rendering of ankle osteoarthritis

No Love for PRP in Ankle Osteoarthritis Trial

Dutch researchers throw cold water on popular therapy

The packaging and vials of Benlysta (belimumab)

Following Rituximab With Second Biologic Helpful in Lupus

Trial may provide answer for patients who don't respond to B-cell depletion

A close up of a man scratching the psoriasis on the back of his hand

How Should Patients With Autoimmune Diseases Approach COVID Vaccination?

Mixed messaging and a lack of tailored research leaves providers and patients in the dark

FDA APPROVED adalimumab-adbm (Cyltezo) over a photo of a woman using an auto injector syringe.

First Interchangeable Humira Biosimilar Approved

Cyltezo nabs coveted "interchangeable" status for RA, inflammatory bowel disease, and more

FDA APPROVED avacopan (Tavneos) over a photo of a man鈥檚 foot showing vasculitis.

FDA Gives Thumbs Up to ANCA-Associated Vasculitis Drug

Approval granted to avacopan despite advisory committee concerns

ASBMR over a computer rendering of a human skeleton

Is This the Future of Corticosteroids?

Novel agent, aimed at doing away with adverse metabolic effects, proves mettle in DMD

A photo of a woman attempting to smell half of an orange.

Olfactory Loss Common in Sjogren's Syndrome

Objective impairments in olfaction correlated with disease activity and symptoms

A young boy curled up on the sofa with stomach pain.

IBD and Pediatric Arthritis: Exploring the Link

Risk factors include enthesitis, family history, and etanercept use

A micrograph of pneumocystis (carinii) jiroveci

Pneumocystis Often Lethal in Dermatomyositis

Incidence of pneumonia high in MDA5-antibody-positive patients

An image of of package of Xeljanz

FDA Slaps Restrictions on JAK Inhibitors Over Serious Safety Risks

Use for inflammatory conditions limited to those who fail on TNF blockers

Photo of 72-year-old woman being evaluated for mild pain and joint stiffness in her hand.

What's Causing Cancer Patient's Joint Pain While on Checkpoint Inhibitor?

Here is how clinicians diagnosed this rare inflammatory side effect

A woman kisses her elderly mother on the forehead in the kitchen.

What Factors Predict RA in First-Degree Relatives?

Study may offer insight into preclinical phase to identify factors that predict progression

A bottle and tablet of Rinvoq (Upadacitinib) over a close up of a man scratching the eczema on the back of his hand

JAK Inhibitor Tops Mab for Eczema

New disease-modifying treatment option on the horizon

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