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News, opinions and meeting coverage in rheumatology.

A photo of bottles of Jyseleca tablets.

Filgotinib Maintains RA Efficacy for 3 Years, No New Safety Issues

Looks like FDA blew the call on selective JAK1 inhibitor

A photo of a female orthopedic doctor performing an ultrasound on a little girl鈥檚 knee.

Old-Line Rheum Drugs Lose Luster in JIA

Treatment patterns shift as new products come on board

A computer rendering of a knee joint highlighted in red.

Another Stab at Disease-Modifying OA Drug Hits Home in Early Study

Taking a page from HIV medicine

A photo of a senior man receiving a COVID vaccination.

Study Offers Clues for Avoiding RMD Flares After COVID Vaccination

European registry analysis brings surprises along with the expected

CHEST over a photo of Boston Convention and Exhibition Center, Boston, MA.

CHEST Roundup: Diabetes in RA Patients Ups Risk of Interstitial Lung Disease

Plus: nalbuphine for IPF cough and AI for reducing lung allograft discards

MRI images of sacroiliac articulation in a patient with ankylosing spondyloarthritis.

AI Does OK, Not Great, for Finding Inflamed Joints in axSpA

While imperfect relative to human experts, system might still be clinically useful

The YouTube thumbnail with Siobhan Deshauer, MD, a photo of skin tags, and the words: HIGH SUGAR.

What Skin Says About Health

Knowing what to look for can mean the difference between life and death

A photo of a female physiotherapist leading a man through knee exercises in a gym.

Exercise, Education to Relieve Knee OA: Mixed Results in Modeling Study

Only limited value when costs are considered, study suggests

A photo of an MRI image of a knee on a monitor with an out-of-focus MRI machine in the background.

In Diagnosing Knee Pain, Sometimes More Is More

MRI does occasionally reveal important findings missed on x-ray

An x-ray image of a child鈥檚 hands.

These Kids With JIA Fare Poorly for Methotrexate Adherence

Family, social, and financial stress compromises treatment, study suggests

A computer rendering of a syringe releasing monoclonal antibodies.

JAK Inhibitors Edge Out Anti-TNFs for Pain Relief in Rheumatoid Arthritis

Swedish study looks at neglected issue in RA treatment

A photo of a woman鈥檚 legs swollen knees and patches of psoriasis from psoriatic arthritis.

Hitting Psoriatic Arthritis Early With Apremilast Helps Some Patients, Trial Finds

But only a minority achieved minimal disease activity within 16 weeks

A photo of a woman self-injecting with an adalimumab injection pen.

Arthritis Patients More Likely to Stick With Biosimilars

Spanish registry data show longer time without discontinuing; reasons unclear, however

A computer rendering of a macrophage and blood cells.

Novel Drug Works Near-Miracle for sJIA Patients With Life-Threatening Complication

Compassionate use produces dramatic results in two patients with juvenile idiopathic arthritis

A computer rendering of a transparent human body with the kidneys highlighted.

Renal Impairment Tracks With Rheumatoid Arthritis Disease Activity

Study highlights another reason to keep RA under control

Medicare Unveils First 10 Negotiated Drug Prices

Prices slashed by as much as 79%

Methotrexate for Knee Osteoarthritis; Evaluating Squamous Cell Cancers

Also in TTHealthWatch: blood tests for Alzheimer's

A computer rendering of the palmar face of the hand and its contents: median nerve, tendons, radial artery.

Study: Hand OA May Affect Tendons Too

But clinical importance remains uncertain

A photo of a senior woman holding a pill organizer.

Economic, Personal Burden of RA: Maybe Not So Bad?

Survey data show increased healthcare costs, functional impairment, but not as much as expected

A photo of a woman drawing from a vial of Remicade.

Medicare Lags, Medicaid Leads for Biosimilar Uptake

Infliximab copycat usage varies widely with payer type

Superior migration of humeral head

Make the Diagnosis: There are Lots of Clues, but Can You Make the Diagnosis?

A 68-year-old man presented to the doctor with complaints of right shoulder pain, joint stiffness, and decreased range of motion that developed over the last 2 months. Can you diagnose the patient?

A photo of a mature woman鈥檚 knee x-ray on a monitor as she meets with a female rheumatologist in the background.

Osteoarthritis Diagnosis Portends Sickly Later Life

20-year study portrays OA as risk factor for multiple comorbidity

A computer rendering of periodontitis.

Wait, Maybe Periodontal Disease Doesn't Promote Rheumatoid Arthritis (or Vice Versa)

Danish study suggests surprising explanation for association

A close up photo of broccoli soup.

Really, Soup Might Help in Osteoarthritis?

Not just any soup. And no chicken needed.

A computer rendering of test tubes of blood lying on a test form.

Use This Common Cardiac Test in RA Patients, Study Suggests

Identifies heart risks not captured by conventional risk factors

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Izokibep Marches on for Psoriatic Arthritis

Early phase III data cement case for novel IL-17A inhibitor

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

OA Patients Get Long-Term Benefit From Lifestyle Improvements

Improvement in pain and function lasted well after formal program ended

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Is 'Difficult-to-Treat' RA a Lost Cause?

The name says it all, but progress appears to be coming

A close up photo of a Humira prefilled syringe.

Humira Clobbers Biosimilars in Battle for Part D Coverage

Pricing, payer policies keep market leader on top

A photo of a bottle of Olumiant tablets.

JAK or TNF Inhibitor as First Targeted Drug for Rheumatoid Arthritis?

Pragmatic head-to-head study finds a winner, with caveats

A photo of a senior woman grimacing while clutching her painful wrist.

In RA, Poorly Controlled Pain Portends Even More Serious Problems

Australian study documents risks for life-threatening complications

A photo of Antarctic krill.

Krill Oil Fails in New Osteoarthritis Trial

Now the question is how to reconcile this study with others finding a benefit

A photo of the tablet, container, and packaging of Rinvoq.

One-Year Data Back Upadacitinib for Clinical Spondyloarthritis

Adds to 14-week results that powered FDA approval for non-radiographic axial spondyloarthritis

A photo of a man receiving a knee injection by a male physician.

Stem Cell Injections in Mexico Led to Drug-Resistant Infections

Three patients acquired Mycobacterium abscessus infections after medical travel

A photo of a bottle of hydroxychloroquine tablets.

Retinopathy With Long-Term HCQ Use: Large Study IDs Risk Factors

Hint: it's not just the cumulative dose

A computer rendering of pliers extracting a tooth from a lower jaw.

Missing Teeth and Joint Pain? RA May Be Imminent

You may not even have to ask if patient has had periodontal disease

A photo of runners in the Brooklyn half and full Marathon in New York City.

Study: Skinny-Leg Runners Face Higher Rates of Knee Arthritis

Questions about risks from weight-bearing activities may now be settled

A photo of a mature man massaging his knee.

Hands-On Treatment May Help in Knee Osteoarthritis

And patients can administer it themselves

A photo of a young male fitness trainer guiding his senior female client through a step exercise.

Here's a Good Exercise Option for Hip OA

Program emphasizing balance and stability equals strength-directed training

A photo of a senior rheumatologist discussing hand x-rays with his female patient

Study: Treat-to-Target Success in Early RA Is Durable

Good outcomes generally maintained for up to two decades

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