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News, opinions and meeting coverage in primary care.

Side by side photos of President Joe Biden and former President Donald Trump

Trump, Biden, and Cognition

Diagnosing impairment requires careful assessment by trained clinician, says Jason Karlawish, MD

A photo of bottles of galantamine supplement capsules.

Alzheimer's Supplements Fail Compared With Generic Drugs

Prescription galantamine drugs were labeled accurately, but dietary supplements were not

A photo of a hospital palliative care unit sign.

Palliative Care Has a Branding Problem

Changing how it's perceived can break down silos

A computer rendering of nerve cells affected by Alzheimer鈥檚 disease.

Alzheimer's Biomarkers Show Specific Changes 20 Years Before Diagnosis

CSF and imaging markers changed in a temporal sequence

A photo of seniors playing pickleball outdoors.

Net Danger? Ophthalmologists Have Their Eyes on Pickleball

While it's not as risky as many other sports, growing pastime still spawns optical injuries

A photo of foods rich in thiamine

Dietary Thiamine Linked With Cognition

J-shaped curve emerges between vitamin B1 in diet and cognitive decline

Computer renderings of COVID, RSV, and flu viruses

When It Comes to Isolation, COVID Shouldn't Be Singled Out From the Pack

It's time for CDC to update its guidance

A photo of a senior woman receiving a covid vaccination at a drive through clinic.

Do We Simply Not Care About Old People?

The pandemic was a wake-up call on how we care for older adults

AAOS over a photo of Moscone Center in San Francisco, CA

Looking for Source of Knee Implant Failure? Biomarkers May Help

Blood or synovial fluid tests can help pinpoint what went wrong, studies suggest

A photo of boxes and blister packs of Paxlovid

COVID's Latest Adaptation: It Has Lulled Us to Sleep

My doctor's refusal to prescribe "just-in-case" Paxlovid speaks volumes

AAOS over a photo of Moscone Center in San Francisco, CA

Clear Opportunity to Identify Patients With Osteoporosis Commonly Missed

Hip surgeons could, but mostly don't, send at-risk patients for screening

AAOS over a photo of Moscone Center in San Francisco, CA

Study: Let's Revisit Extended Antibiotic Prophylaxis in Joint Replacement

One center's experience puts recent policy in doubt

A photo of a Prolia auto injector

Denosumab Protective Against Diabetes?

Study found lower diabetes incidence with osteoporosis drug for patients who stayed on treatment

A computer rendered cutaway of a blood flowing through a vessel

Dementia Predicted 10 Years Before Diagnosis

Blood proteins identified those at risk for all-cause, Alzheimer's, or vascular dementia

AAOS over a photo of Moscone Center in San Francisco, CA

Could Weight-Loss Drug Improve Hip Replacement Outcomes?

Two studies, two conclusions

A photo of PDE5 inhibitor erectile dysfunction drugs

Erectile Dysfunction Drugs Tied to Less Alzheimer's Risk

Large U.K. study tracked health records of 270,000 men

A microscope image of uric acid crystals

Early Marker Found for Long-Term Gout Flare Potential

And the bad news: urate-lowering therapy seemed to make no difference

A computer rendering beta amyloid accumulating between neurons

Even With Alzheimer's Pathology, Healthy Lifestyles May Preserve Cognition

More data support the idea of "cognitive reserve"

A computer rendering of a diseased liver.

Undiagnosed Liver Disease May Be Common in Patients With Dementia

Hepatic encephalopathy could be contributing to cognitive symptoms, study suggested

A photo of the packaging and vial of Aduhelm.

Controversial Alzheimer's Drug Abandoned

Biogen will stop developing and selling aducanumab

A photo of a young male doctor sitting across the desk from his senior female patient.

Some 'Choosing Wisely' Recs Protect Older Folks From Low-Value Care

Study looked at how three recommendations changed primary care decisions

A photo of a frozen pizza in an electric oven.

Dietary Factors Tied to Osteoarthritis Pain

But radiographic parameters not affected, raising questions about the link

Cancer After Weight Loss; How Older Adults Use the Healthcare System

Also in TTHealthWatch: PFAS guidelines for clinicians

A computer rendering of neurons containing Lewy bodies

New Parkinson's Definition Proposed Based on Biomarkers

Framework focuses on the biology of Lewy body diseases

A photo of a female nurse hugging her senior female patient at they sit on her bed together.

A Reminder of the Value of Hospice

What it is, what it isn't

A photo of the box of and blisterpack of diazepam tablets lying on the prescribing information

Benzodiazepines Tied to Worse Outcomes in Progressive Supranuclear Palsy

Drugs are commonly prescribed to treat insomnia, anxiety in PSP

A photo of a senior man walking on the beach in Australia

Adults Who Cite Walking Difficulty Face Higher Fracture Risk

Australian study suggests walking ability can help identify candidates for more assessment

A photo of gabapentinoid capsules in the palm of a man鈥檚 hand.

Gabapentinoid Use Continues to Climb

Gabapentin still commonly prescribed off-label for chronic pain

A photo of a tube of blood labeled Alzheimer鈥檚 disease held in blue rubber gloved hands in front of MRI images of a brain.

Alzheimer's Blood Test Shows High Diagnostic Accuracy

Commercial ptau-217 assay reduced confirmatory testing by about 80%

A photo of the Prolia auto injector and packaging.

FDA Slaps Boxed Warning on Osteoporosis Drug

Denosumab can cause severe hypocalcemia in patients with advanced CKD, agency finds

A photo of a car buried in deep snow during a blizzard in Davis, West Virginia.

Lovely Winter, the Killer

It's miserable for the weak, the sick, and the poor

A computer rendered cutaway of a spine affected by osteoporosis

Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis

New findings led to boxed warning on drug's labeling for advanced CKD patients

An x-ray of a patient with an implanted biventricular pacemaker

Lives Prolonged for Longtime CRT-D Users With Heart Failure

Survival benefit with cardiac resynchronization therapy durable out to 14 years

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Kate Middleton Hospitalized; Sen. Paul Urges Prison for Fauci; COVID Back in Class

Health news and commentary from around the Web gathered by 51成人动漫 staff

A photo of people walking through a snowy Times Square in NYC.

Blinded by the Light? Outdoor Illumination Tied to AMD

Korean study suggests a link

A photo of hands holding a Viagra pill and a glass of water.

Erectile Dysfunction Drugs Plus Nitrates Still a Losing Combination, Study Shows

Cardioprotective effect of PDE5 inhibitors did not pan out with anti-anginals in the picture

A photo of two faceless mannequins.

Face Blindness Is Not Always Permanent

Largest study to date looks at inability to recognize familiar faces

A photo of President Joe Biden walking down the stairs from Air Force One.

Is President Biden a Super-Ager?

Experts say "age is a number, not a quality" -- even for the president

A photo of a female physical therapist leading her male client through exercises three months after knee replacement surgery

Non-White Military Members With OA Get Stiffed for Knee Replacement

Wide racial disparities in a health system that boasts equal access for everyone

A composite image of an Amsler grid laying over a photo of a persons eye

Dementia Drugs Seen Lowering Risk for Macular Degeneration

But not by very much or very quickly, VA analysis finds

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