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News, opinions and meeting coverage in primary care.

A close up of a baby being carried by his mother

Reproductive Life Span of U.S. Women Increasing

Changes in age at both menarche and menopause, study of women followed over 6 decades shows

A blister pack of pills next to a home blood pressure monitor

No Cancer Risk With Commonly Used Blood Pressure Meds

Largest analysis yet but definitive data remain elusive

ENDOBREAK centered between 8 illustrated body organs.

Tepezza Restock Coming; Osteoporotic Fractures Broken Down by State

News and commentary from the endocrinology world

A patient points to a heart diagram on a clipboard held by a cardiologist

Language Matters During This 'Exciting Time' in Heart Failure

A rethinking of what heart failure is and how to communicate with patients

Printed results of a bone mineral density test lay on a desk

Just How Many Older Folks Have Osteoporosis?

A lot, and prevalence is growing

Ophthalmoscopy of glaucoma

Eyes Offer Window Into Cognitive Impairment

Glaucoma study provides more evidence of common neurodegenerative pathway

A conceptual image of a senior Asian man with his hand on his forehead and his mind disintegrating into particles

Dementia Diagnoses Lag in Ethnic and Racial Groups

Asian, Hispanic, Black people diagnosed at later stages than white people

A computer rendering of monoclonal antibodies

FDA Panel Unhappy With Novel OA Pain Drug

Latest setback for troubled osteoarthritis biologic

A female doctor takes the blood pressure of her mature female patient, both are wearing protective masks

Hypertension After COVID Vax No Cause for Worry, So Far

Disagreement over special precautions for individuals with high BP

A man wearing a party hat sits alone at a table in front of a birthday cake

Middle-Age Loneliness Linked to Alzheimer's Disease

Relationship varied, depending on whether loneliness persisted

ENDO over a computer rendering of a woman in silhouette with her thyroid and pituitary glands highlighted

ENDO 2021 Roundup: Jatenzo Liver Data, Adrenal Insufficiency, and More

Other noteworthy research presented at the Endocrine Society's annual meeting

What to Make of That Danish Reinfection Study?

Vinay Prasad, MD, MPH, discusses the findings and their takeaway

Vials of Leukine (sargramostim) sit atop their packaging

Marrow Cell Stimulator to Treat Alzheimer's Disease?

Unusual approach pans out in mid-stage trial

4 blue generic erectile dysfunction pills

Choice of Erectile Dysfunction Med May Have Heart Health Implications

Large observational study of PDE-5 inhibitors vs alprostadil

Brain scan images with NeuroBreak in the center.

Bacon and Dementia Risk; Zinc Fingers and Tau; Older Adults Light Up

News and commentary from the world of neurology and neuroscience

ISC over a computer rendering of a male figure with the front of his brain highlighted by a flash of light

Loop Recorder Proves Mettle in Broader Stroke Population

STROKE AF trial supports use outside of cryptogenic stroke category

ISC over a computer rendering of a male figure with the front of his brain highlighted by a flash of light

Immediate Angiography Feasible for Large Vessel Stroke Patients

Not stopping patients in the ED improved hospital workflow and patient outcomes

Why Women Experience COVID and the Vaccines Differently Than Men

It's chromosomal and hormonal, and maybe sociocultural too

A vial of ocrelizumab (Ocrevus) next to an MRI image of progressive multifocal leukoencephalopathy (PML)

PML Reported in Ocrelizumab-Treated MS Patient

Case raises questions about treatments for older people with multiple sclerosis

A pile of yellow gel capsules

Skip These Supplements for Afib Prevention

Long-term results from the VITAL Rhythm study in a large population

An African-American male wearing an oxygen mask lies in a hospital bed

Uneven Progress Closing Race Gap in Heart Health

Urban areas more successful at narrowing disparities

A computer rendering of a coagulated clot of red blood cells entangled in fibrin

Op-Ed: COVID Shot While on a Blood Thinner?

One hematologist's strategy for addressing concerns

A woman鈥檚 hand holds a swab and specimen container from a COVID-19 Home Test kit on her lap

Pathologists Urge Caution on At-Home COVID Test Kits

"Did it sit in the sun?"

Photo of Iora Health co-founder Rushika Fernandopulle, MD (Photo courtesy Iora Health)

Healthcare Disruptors: Doubling Down on Primary Care

Iora Health and its care teams are changing the way primary care is delivered

When Can I Walk Into a Pharmacy and Get a COVID Shot?

Walgreens' Rina Shah, PharmD, on the challenges and opportunities

A senior woman in front of her open medicine cabinet using a pill organizer

Dementia Patients Often Have Dangerous Mix of Drugs at Home

Combinations increase risk of falls, respiratory suppression, cognitive impairment

An ECG of a heartbeat over a close up of a man clutching his chest

Universal Definition of Heart Failure Proposed

U.S., European, and Japanese societies seek to standardize classifications

Apples, grapefruit, oranges, pears, kiwi, lemons, and limes line the shelves at a grocery store.

And the Magic Number for Daily Fruit, Vegetable Intake Is...

No benefit to peas, corn, potatoes observed in cohort studies

A close up of a senior man and woman embracing, her hand on his cheek

Ethics Consult: Does Dementia Preclude 'Consent' to Sex? MD/JD Weighs In

You voted, now see the results and an expert's discussion

AAN over several MRI scans of a brain

Alzheimer's May Start Sooner for People With Anxiety, Depression History

Psychiatric disorders could have additive effects on AD pathophysiology, study suggests

A photo of the Zio XT wearable ECG patch

ECG Patch Boosts Afib Diagnoses in Older Folks

But unclear if it's clinically beneficial

The packaging and syringe of Kineret (anakinra) over a microscope image of uric acid crystals

Anakinra for Gout Flares: Is There a Role?

IL-1 blockade was not superior to triamcinolone, but does have advantages

The vials and packaging of Opdivo (nivolumab) and Yervoy (ipilimumab) for injection

Neoadjuvant Dual ICI Leads to Clinical Benefit in Operable NSCLC

More than one-third of patients achieved major pathologic response with nivolumab-ipilimumab.

Can the Same Vaccines Protect Against New COVID Strains?

Questions about long-term efficacy become more insistent

FDA APPROVED Sacubitril/valsartan (Entresto) over a photo of a man clutching his chest which is highlighted in red

First Drug Approved for Some HFpEF

FDA doesn't set hard limits on ejection fraction in expanded indication

Brain scan images with NeuroBreak in the center.

Sleep-Dementia Link; Neanderthal Mini-Brains; MS Tx and COVID Vax

News and commentary from the world of neurology and neuroscience

GuCS over a computer rendering of the genitourinary system

CCR Score Could Offer ADT-Free Path in Higher-Risk Prostate Cancer

Large proportion of intermediate- to high-risk patients could avoid aggressive therapy

GuCS over a computer rendering of the genitourinary system

Radionuclide Tx Wins in Third-Line Metastatic CRPC

Early trial shows improved PFS, response rates versus cabazitaxel

GuCS over a computer rendering of the genitourinary system

Hit and Miss in Castration-Resistant Prostate Cancer

No OS benefit with apalutamide-abiraterone, despite improved PFS

A photo of the top of a balding man鈥檚 head showing actinic keratosis

Want Data on Recently Approved Actinic Keratosis Drug? Here You Go

Phase III trial now published in full for topical anti-proliferative treatment

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