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Seizures

News, opinions and meeting coverage in neurology.

Human Birth Defects Seen With Pregabalin

Time for a pregnancy category change?

Everolimus May Have Activity in Seizure Disorder

Drug reduced seizure frequency in tuberous sclerosis compared with placebo

Once-Daily Epilepsy Tx Shows Promise

Eslicarbazepine non-inferior to twice-a-day carbamazepine

Clot-Buster Is a Bust in IVH Study

The study failed but the patients lived. What next?

Wired for Life: Device Short Circuits Seizures

When nothing else works, this device may be best option in epilepsy

Continuous Tx May be Problematic in Status Epilepticus

Longer PICU stay, more vasopressor use with continuous versus bolus therapy

Still Only Open-Label Evidence for Cannabis Drug

Data from randomized controlled trials expected in February

Rivermead Test: More Sensitive to Memory Loss in Epilepsy?

Small study suggests new test can measure decline over time

One Patient's Seizure Cure: Stop Solving Sudoku Puzzles

Hypoxia suffered after an avalanche leads to puzzle-solving problem

Stroke Rounds: Seizures More Common in Afib

Stroke prediction score also predicts seizure risk in afib patients

Guideline: Managing Unprovoked First Seizures in Adults

Anti-epileptic drugs may reduce risk of recurrence, joint AAN-AES guideline says.

Cannabis for Child Seizures: Popular, But Is It Effective?

Thus far, only parent reports and open-label trials for support.

Drugmaker: Aptiom Monotherapy Cuts Seizures

Study supports FDA filing for expanded indication.

Benefits Pile Up for Epilepsy Surgery

When surgery is an option, studies suggest it's usually the best one.

Women on Seizure Meds Need More Folic Acid

WASHINGTON -- About half of epileptic women taking anti-seizure drugs who could have become pregnant said they were not taking the recommended folic acid supplements, results of a survey found.

At-Home Seizure Tests Promising

WASHINGTON -- Technologies to provide instant at-home detection of life-threatening seizures and that could allow epilepsy patients to monitor their own drug levels are almost ready, researchers said here.

Satisfaction With Epilepsy Surgery Lasts Long Term

WASHINGTON -- More than 90% of patients who had surgery for drug-resistant epilepsy said it was worthwhile when interviewed up to 20 years later, even when quality-of-life indicators were not improved, researchers said here.

Laser Epilepsy Surgery Boosts Memory Function

WASHINGTON -- Stereotactic laser ablation of seizure foci in the hippocampus appeared to reverse certain types of memory deficits that commonly occur in this population, researchers said here.

Striking a Nerve: Heinz Kerry Recovers

Teresa Heinz Kerry is back at work less than 4 months after a mysterious seizure hospitalized her. Striking a Nerve is a blog by John Gever for readers interested in neurology.

Data Supports Eslicarbazepine in Epilepsy

VIENNA -- Pooled phase III study results on eslicarbazepine acetate, a prodrug for S(+)-liscarbazepine, showed that the drug outperformed placebo as add-on therapy for partial-onset seizures in adults, a researcher said here.

Injector Pen May Ease Emergency Seizure Tx

SAN DIEGO -- An investigational pen-type injector for delivering intramuscular diazepam appeared safe and effective for home treatment of acute seizures, researchers said here.

Child's Epilepsy Keeps Household Up All Night

Children with epilepsy and their parents reported suffering from sleep problems, researchers found.

Lacosamide Good in Trigeminal Neuralgia

NEW ORLEANS -- The anti-epileptic agent lacosamide (Vimpat) appears to give relief to patients with refractory trigeminal neuralgia, researchers reported here.

Antidepressants May Help Cut Seizures

NEW ORLEANS -- Patients with epilepsy who experience more than one seizure a month appear to achieve a reduction in seizure activity when treated with antidepressants, researchers reported here.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

India Emerges as Source for Execution Drugs

Unable to get Pentothal through regular channels, Nebraska prison officials turned to a broker in India so they could execute two convicted murderers.

Two-Drug Combo Appears Best for Refractory Epilepsy

For patients with refractory epilepsy, a combination of lamotrigine and valproate may be the best option for preventing seizures, a retrospective analysis showed.

New Warning on Valproate Drugs in Pregnancy

Labels for valproate sodium and related drugs for epilepsy will carry new language warning that children exposed to these agents during gestation may suffer cognitive deficits, the FDA said.

The Eyes May Reveal Epileptic or Psychogenic Seizures

PHOENIX, Ariz. — A simple but reliable way to distinguish psychogenic nonepileptic seizures from epilepsy is to look at the patient's eyes, researchers here reported.