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General Neurology

News, opinions and meeting coverage in neurology.

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Polypill Looks Good for Parkinson's

Fixed-dose product combining two standard drugs outperforms each alone in phase III

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Trofinetide Shows Promise in Rett Syndrome

Investigational drug demonstrates modest benefit for primary, secondary endpoints

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Myasthenia Gravis: Better Version of Eculizumab on the Horizon

Phase III study paves way for new ravulizumab indication

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Novel Wrinkle on Botulinum Toxin Succeeds for Cervical Dystonia

Formulated for longer activity, symptoms stay suppressed until time for next dose

A photo of Bruce Willis.

Bruce Willis' Aphasia

Why the award-winning actor is stepping down from the big screen

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Stroke While on LVAD No Barrier to Successful Heart Transplant

It doesn't help, for sure, but it doesn't seem to hurt greatly either

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Prion Disease on the Rise in the U.S.

Now the question is, why?

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Persistent Brain Fog After Mild COVID Infection Tied to CSF Markers

Immune activation, immunovascular markers elevated in people with long COVID cognitive changes

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Could Undiagnosed Neuro Condition Explain Grandpa's Falls?

Peripheral neuropathy found in many patients who weren't aware of it

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Endovascular Brain-Computer Interface Safe, Effective in ALS

No serious adverse events with novel device at 1 year

A computer rendering of antibodies attacking a COVID virus.

What Drives Post-COVID Cognitive Changes?

New research hints at why COVID brain fog may persist

FDA ADCOMM sodium phenylbutyrate + taurursodiol (AMX0035) over a computer rendering of a disintegrating motor neuron.

ALS Drug Needs More Evidence, FDA Advisors Say

But vote was close and panelists remain hopeful about AMX0035

A photo of the vial and packaging of Aduhelm.

Aducanumab Data Finally Published, but Alzheimer's Experts Spot Problems

Questions raised about secondary endpoints

A fundus camera image of the retina showing acute non-proliferative diabetic retinopathy.

Diabetic Eye Disease Linked With Neurodegenerative Disorders

Future risk of systemic neurodegeneration, particularly cognitive impairment, more than doubled

A victims eye view of a man with no face in a hooded sweatshirt with his fists raised

Once Taboo, Study Examines Violence to and by People With Tourette or Chronic Tics

"Hesitancy to open Pandora's box," but information may be vital to help patients, families

Doctor Sued Over Stem Cell Treatments

Clinic made almost $750K from treatments with no evidence behind them

Brain scan images with NeuroBreak in the center.

Sleep and Light Exposure; Patients Protest CMS Plan; Lamotrigine's Cardiac Risks?

News and commentary from the world of neurology and neuroscience

A senior woman sitting in bed massages her toes.

Peripheral Nerve Problems Tied to Later Dementia

Findings may indicate shared susceptibility to neurodegeneration

A photo of Gregory Poland, MD

Vaccine Researcher Who Developed Tinnitus After COVID Shot Calls for Further Study

Gregory Poland, MD, advocates both vaccination and better understanding of possible side effect

A close up of a healthcare workers blue rubber gloved hand about to give a woman a COVID vaccination.

Neurologic Complications Rare After COVID-19 Vaccines

Seizures after adenovirus vaccine emerge in VAERS reports

Medical staff members from Jiangsu Province work at an ICU ward of the First Hospital of Wuhan City in Wuhan, central China

Cognitive Effects Persist in Older COVID Patients

Long-term cognitive decline common after SARS-CoV-2 hospitalization

A portrait of a mature man cupping his ear with his hand in an effort to hear.

Hearing Loss, Epilepsy May Be Early Signs of Parkinson's Disease

Known symptoms like tremor spotted in primary care records 10 years before diagnosis

A computer rendering of covid viruses attacking a person鈥檚 brain.

Brain Changes Seen After Mild COVID Infection

Tissue damage, brain shrinkage, cognitive decline emerge in longitudinal study

A close up of a mature couple clinking their wine glasses together.

Brain Volumes Shrink With One Daily Drink

Even light to moderate alcohol intake shows effects

A computer rendering of antibodies attacking a neuron.

Cancer May Heighten Odds of Guillain-Barre Syndrome

Link strongest with hematologic malignancies as well as prostate, breast, and respiratory cancers

A photo of a woman sitting on a rug and holding her painful foot which is highlighted in red.

Nerve Damage May Contribute to Long COVID Symptoms

Small-fiber neuropathy may stem from defective immune response to SARS-CoV-2

ACTRIMS over a photo of Palm Beach County Convention Center

MS Patients on Cladribine Show Fewer Relapses

Real-world data analysis compares oral disease-modifying therapies

A sad looking teen girl looking at a smartphone in her darkened bedroom.

Tic Severity in Teens Rises With Social Media Use During Pandemic

Study adds to findings linking tics and tic-like behaviors with possible pandemic stress

ACTRIMS over a photo of Palm Beach County Convention Center

Stem Cell Transplantation Shows Benefits in Aggressive MS

No new relapses recorded after autologous transplant

ACTRIMS over a rendering of a vein

Deep Learning Identifies PPMS Patients Who May Respond to Treatment

Predictive enrichment could increase the power of future trials

ACTRIMS over a photo of Palm Beach County Convention Center

Paramagnetic Rim Lesions Highly Specific in MS Diagnosis

Sensitivity, accuracy also high in prospective study

ACTRIMS over a photo of Palm Beach County Convention Center

COVID Vax Response Still Impaired in Some MS Patients After Third Shot

Subset of multiple sclerosis patients seroconverted after third dose, however

An otolaryngologist examines the ear of a young male.

Sudden Hearing Loss After COVID Shot: Slight Risk or Just Noise?

Reports continue to be rare, but potential links may need further study

A cartoon illustration of the figure: $269/hr pointing to a female doctor and $89/hr pointing to a sad male physician.

10 51成人动漫 With the Lowest Hourly Rate

Calculated by annual salary divided by number of hours worked

A nurse tends to a senior comatose man in the ICU.

Comatose Cardiac Arrest Survivors Don't Need Brain Misfires Suppressed

Trial finds seizure meds unwarranted for aberrant EEG patterns in the ICU

A photo of Bob Saget.

Bad Falls and Bad Calls: Speculation on Bob Saget's Death

Second-guessing the forensic pathologist was bad science and lazy journalism

A computer rendering of a seizure EEG over a brain with the center highlighted.

Early Seizures After Traumatic Brain Injury Tied to Epilepsy, Mortality

TBI severity, prior comorbidities up risk of early seizures

A photo of paramedics tending to a man on a stretcher with a head injury

Cognitive Effects Persist After Concussion

At 1 year, poor cognitive outcomes were common in people with mild TBI

Brain scan images with NeuroBreak in the center.

Cialis and Brain Blood Flow; Sleep and Media Use; Can Tarantulas Solve Chronic Pain?

News and commentary from the world of neurology and neuroscience

A photo of a pregnant woman sitting on her bed holding a glass of water and a green pill.

Blood Levels of Common Epilepsy Drugs Drop During Pregnancy

Antiseizure medication monitoring should begin early, researchers say

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