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NeuroBreak: China Bans Designer Opioids; Support for the Amyloid Hypothesis

— News and commentary from the world of neurology and neuroscience

MedpageToday

China said it will , including U-47700, which have been blamed for contributing to overdose deaths in the U.S. The drugs have been a "legal" alternative to fentanyl and carfentanil as regulators haven't been able to keep pace with their creation. (Associated Press)

Teva has (lot 1160682A, NDC 0591-3693-19) that failed to dissolve properly, which could prevent the drug from reaching therapeutic levels in the body -- and become an insufficient treatment for schizophrenia and schizoaffective disorders, the agency warned. The 3-mg, 90-count bottles, with an expiration of June 2018, were distributed under the Actavis Pharma label. (FDA)

Support for the amyloid hypothesis: A in the amyloid precursor protein (APP) gene is tied to reduced blood levels of beta-amyloid. (Alzforum)

The FDA has for the treatment of ADHD in young patients age 6 to 17. Drugmaker Neos Therapeutics says it is the only methylphenidate extended-release, orally disintegrating tablet for the condition.

rose 75% for women between 2005 and 2014, outpacing a 55% increase seen among men. (AHRQ)

Only one in four young people with opioid use problems were treated with addiction medications, potentially indicating an unmet need, though data have been lacking. (51˶)