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How the Brain Clears Waste; Masked Benzodiazepine Taper; New Hope for PML

— News and commentary from the world of neurology and neuroscience

MedpageToday
Neuro Break over a computer rendering of neurons.

Imaging in neurosurgery patients showed how the clears waste. (PNAS)

Investigational apitegromab of motor function improvement in a phase III trial of spinal muscular atrophy, Scholar Rock announced.

Masked tapering with a targeted behavioral intervention helped older adults with insomnia receptor agonists, a randomized trial showed. (JAMA Internal Medicine)

A case series suggested that directly isolated allogeneic virus-specific T cells may reduce mortality and improve functional outcomes in . (JAMA Neurology)

The BBC offered a close-up .

And Nature published a of the 140,000 neurons in the fruit fly brain.

Long-term associated with inflammation were seen on 7T MRI in a study of people who had been hospitalized with severe COVID-19 early in the pandemic. (Brain)

A barrier to tofersen (Qalsody) treatment appears to be in patients with amyotrophic lateral sclerosis (ALS), researchers argued. (JAMA Neurology)

Researchers proposed areas for using lessons learned from therapeutic development in multiple sclerosis. (Nature Reviews Neurology)

Investigational dalzanemdor compared with placebo in a phase II study of early Alzheimer's disease, Sage Therapeutics said. The drug is also being studied in Huntington's disease.

  • Judy George covers neurology and neuroscience news for 51˶, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.