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Isolation and Dementia Risk; High-Intensity Exercise and the Brain; Migraine and MS

— News and commentary from the world of neurology and neuroscience

MedpageToday
Neuro Break over a computer rendering of neurons.

Being socially isolated was associated with a 28% over 9 years, data from the National Health and Aging Trends Study showed. (Journal of the American Geriatrics Society)

Six minutes of high-intensity exercise (BDNF), a protein involved in neuroplasticity, in 12 aerobically fit healthy young adults. (Journal of Physiology)

Manipulating gut microbiota in a mouse model of tauopathy led to a , tau pathology, and brain damage that was sex- and APOE-dependent. (Science)

After reports of in spinal muscular atrophy patients treated with onasemnogene abeparvovec (Zolgensma), the European Medicines Agency is preparing updated recommendations for the gene therapy.

Whistleblowers at the Journal of Clinical Investigation must after a group who flagged research about simufilam, Cassava Sciences' investigational Alzheimer's drug, allegedly profited from short-selling Cassava stock. (Nature)

Walking pace was over a median follow-up of 12 years, U.K. Biobank data showed. (Alzheimer's Research & Therapy)

Whether people were was related to inherent differences in brain structure and function of frontoparietal networks, a MRI study suggested. (Human Brain Mapping)

Researchers identified 69 genes carrying somatic brain mutations in that cause intractable epilepsy. (Nature Genetics)

A new phase II trial will evaluate the investigational treatment with a lower burden of Huntington's disease, Ionis Pharmaceuticals announced.

Is migraine a risk factor for ? (Neurology)

An essayist reflected on her family's decision to to Alzheimer's research. (Time)

  • Judy George covers neurology and neuroscience news for 51˶, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.