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First U.S. Case of Bird Flu in a Pig Raises Concerns Over Threat to Humans

— The infection happened at a backyard farm

MedpageToday
An electron microscope image of an avian influenza A H5N1 virion.
(Cynthia Goldsmith, Jackie Katz/CDC via AP, File)

A pig at an Oregon farm was found to have bird flu, the U.S. Department of Agriculture (USDA) Wednesday. It's the first time the virus has been detected in U.S. swine and raises concerns about bird flu's potential to become a human threat.

The infection happened at a backyard farm in Crook County, in the center of the state, where different animals share water and are housed together. Last week, poultry at the farm were found to have the virus, and testing this week found that one of the farm's five pigs had become infected.

The farm was put under quarantine and all five pigs were euthanized so additional testing could be done. It's not a commercial farm, and U.S. agriculture officials said there is no concern about the safety of the nation's pork supply.

But finding bird flu in a pig raises worries that the virus may be hitting a stepping stone to becoming a bigger threat to people, said Jennifer Nuzzo, DrPH, a Brown University pandemic researcher.

Pigs can be infected with multiple types of flu, and the animals can play a role in making bird viruses better adapted to humans, she explained. The 2009 H1N1 flu pandemic had swine origins, Nuzzo noted.

"If we're trying to stay ahead of this virus and prevent it from becoming a threat to the broader public, knowing if it's in pigs is crucial," Nuzzo said.

The USDA has conducted genetic tests on the farm's poultry and has not seen any mutations that suggest the virus is gaining an increased ability to spread to people. That indicates the current risk to the public remains low, officials said.

A different strain of the bird flu virus has been reported in pigs outside the U.S. in the past, and it did not trigger a human pandemic.

"It isn't a one-to-one relationship, where pigs get infected with viruses and they make pandemics," said Troy Sutton, PhD, a Penn State researcher who studies flu viruses in animals.

This version of bird flu -- known as Type A H5N1 -- has been spreading widely in the U.S. among wild birds, poultry, cows, and a number of other animals. Its persistence increases the chances that people will be exposed and potentially catch it, officials say.

It isn't necessarily surprising that a pig infection was detected, given that so many other animals have had the virus, experts said.

The Oregon pig infection "is noteworthy, but does it change the calculation of the threat level? No it doesn't," Sutton said. If the virus starts spreading more widely among pigs and if there are ensuing human infections, "then we're going to be more concerned."

So far this year, nearly have been reported -- in California, Colorado, Washington, Michigan, Texas, and Missouri -- with mostly mild symptoms, including conjunctivitis, reported. All but one of the people had been in contact with infected animals.