Cryoprecipitate, REBOA Flop for Improving Major Hemorrhage Outcomes The first randomized trials of both approaches failed Oct 13, 2023
Rare Lung Bleeds Cluster in DOAC Users, Implications Unclear Pattern found in diffuse alveolar hemorrhage reports in FAERS Oct 11, 2023
Chemo Shortage: 'Paycheck to Paycheck'; Cancer Blood Test Shines; Struggling to Live News, features, and commentary about cancer-related issues Oct 06, 2023
ABIM CEO Retirement Comes Amid Wave of Criticism Richard Baron, MD, plans to step down as pushback against MOC grows Oct 02, 2023
IV Immunoglobulin May Cut Infection Risk of Anti-BCMA Agents for Myeloma Small retrospective study finds fewer severe infections during periods of replacement therapy Sep 29, 2023
Cancer Drug Shortages for Kids; Pharma Agrees to Price Talks; Catch-Up on Screening News, features, and commentary about cancer-related issues Sep 28, 2023
Frontline Combo Yields High Remission Rate in Hairy Cell Leukemia And almost all complete responders in small trial achieved MRD negativity Sep 25, 2023
TikTok Dinged for Misinformation; BRCA Risk Overestimated; Cheers for Oncology News, features, and commentary about cancer-related issues Sep 21, 2023
Another Win for Biomarker-Driven Thromboprophylaxis for Patients With Cancer Threefold risk reduction with enoxaparin in high-risk gastrointestinal, lung cancers Sep 21, 2023
FDA Approves JAK Inhibitor That Addresses Anemia in Myelofibrosis In a phase III trial, momelotinib reduced anemia, constitutional symptoms, and splenomegaly Sep 18, 2023
Weight-Loss Surgery Tied to Lower Blood Cancer Risk in Women Consider surgery for primary prevention in people with obesity, researchers suggest Sep 15, 2023
Cisplatin Shortage Eases; Air Pollution Linked to Breast Cancer; Pap Test Confusion News, features, and commentary about cancer-related issues Sep 15, 2023
Stem-Cell Mobilization Booster Wins FDA Approval for Multiple Myeloma Motixafortide plus filgrastim increased adequate harvest rate from 9.5% to 67.5% Sep 11, 2023
FLT3 Inhibitor Improves AML Survival With or Without Stem-Cell Transplant Best outcomes with transplantation, but non-transplant patients also benefited from quizartinib Sep 11, 2023
High Rate of Durable Responses in R/R Lymphoma With Bispecific Antibody Response rate exceeds 60%, with 15- to 20-month duration with epcoritamab Sep 11, 2023
Study Questions Value of Interim PET Imaging to Guide Frontline Hodgkin Treatment One of 40 patients changed treatment but all remained on brentuximab regardless of scan results Sep 09, 2023
Standard Lymphoma Therapies Tied to Higher Risk for New Malignancies Increased risk for non-melanoma skin cancer, MDS, AML versus the general population Sep 09, 2023
Early Major Response to Ponatinib in Pretreated CML Portends Better Outcomes Molecular or cytogenetic response at 3 months correlated with better survival Sep 08, 2023
Intensive Pretransplant Consolidation in Older AML Fails to Improve Results Newer therapies and strategies might show more promise for boosting survival Sep 07, 2023
Microdevices for Glioma; Cervical Adenocarcinoma Test; Language Gaps and Cancer Care News, features, and commentary about cancer-related issues Sep 07, 2023
More Intense ALL Therapy Improves Outcomes in Adolescents, Young Adults Treatment with "pediatric-inspired protocols" improved event-free, relapse-free survival Sep 07, 2023
Cancer Patients More Likely to Die During COVID Pandemic Omicron wave was especially deadly, and those with blood cancers at increased risk Sep 01, 2023
Prayer to Cure Cancer; Exercise for Sexual Dysfunction; Carb Intake and Cancer News, features, and commentary about cancer-related issues Sep 01, 2023
Novel Oral Tx Shows Early Promise in Relapsed/Refractory Myeloma Mezigdomide led to 41% response rate in heavily pretreated patients Aug 30, 2023
U.S. Unveils First 10 Drugs for Medicare Price Negotiations Treatments for heart failure, Crohn's disease, and diabetes make the list Aug 29, 2023
Adenovirus May Trigger Thrombocytopenia, Thrombosis, Case Studies Suggest First reports of an anti-PF4 disorder associated with an adenovirus infection Aug 09, 2023
Adcetris Plus Chemo Effective in HIV-Related Hodgkin Lymphoma Researchers call study "practice changing," although outside experts urge caution Aug 04, 2023
Anti-PD-1 Alone Produces Durable Responses in Relapsed/Refractory PMBCL More than 80% of responding patients remained in response at 4 years Jul 24, 2023
New Recommendations Address Global Inequality in Sickle Cell Disease Care Commission lays out strategies for progress by 2025 and beyond Jul 13, 2023
Non-Covalent BTK Inhibitor Yields High Response Rate in Pretreated CLL 73% of patients with prior exposure to covalent BTK inhibitors responded Jul 05, 2023
FDA Gives Nod to Gene Therapy for Hemophilia A First gene therapy approved for severe hemophilia A Jun 29, 2023
TXA Holds Its Own for Heavy Menstrual Bleeding in von Willebrand Disease In phase III study, recombinant VWF not superior to cheaper alternative for type 1 and 2 cases Jun 29, 2023
No OS Benefit With Ibrutinib in Early-Stage, High-Risk CLL Study suggests "watch and wait" should remain standard of care Jun 28, 2023
New Bispecific Antibody Approved for Tough-to-Treat Lymphoma Approval of glofitamab was based on a phase I/II study that showed a 56% overall response rate Jun 16, 2023
Base-Edited CAR-T Product 'Potent' in Relapsed Childhood T-Cell ALL One young patient achieved molecular remission within 28 days of infusion Jun 14, 2023
Pre-Existing Depression, Anxiety Tied to Worse DLBCL Prognosis Patients with depression alone had the worst overall survival Jun 13, 2023
CRISPR Therapy Exceeds Targets in Thalassemia, Sickle Cell Disease Results "indicate that exa-cel can provide a one-time functional cure," says researcher Jun 13, 2023
CAR-T for Chronic Lymphocytic Leukemia Hits Goal of Mid-Stage Trial All patients had progressed on BTK inhibitors and most had failed venetoclax Jun 12, 2023
Skipping Radiotherapy 'Seems Safe' for PMBCL Patients in Remission PET-negative patients after chemoimmunotherapy fared well with observation alone Jun 07, 2023
Second-Line Axi-Cel Bests Standard in Relapsed/Refractory Large B-Cell Lymphoma The CAR T-cell therapy led to significantly longer overall survival Jun 05, 2023
