Keytruda Tops Adcetris in Head-to-Head Hodgkin's Trial Checkpoint inhibitor improved PFS in refractory and transplant-ineligible cases Jun 15, 2020
New Standard for Relapsed/Refractory Multiple Myeloma? Triplet regimen significantly extended median PFS versus doublet in IKEMA study Jun 15, 2020
High Marks for CAR T Cells in R/R Myeloma Response rates of 70-100% with BCMA-targeted products for heavily treated disease Jun 03, 2020
Early Palliation: Boon for AML Patients on Intensive Chemo Intervention led to marked improvements in QoL, mental distress, end-of-life care Jun 02, 2020
VRd Still Reigns in Newly Diagnosed Myeloma KRd fails to prove superiority in head-to-head trial Jun 01, 2020
CAR T-Cell Therapy Impresses in Indolent NHL Overall response rate exceeding 90% with axi-cel in relapsed/refractory setting May 31, 2020
Nivolumab-Based Tx Effective in Early, Unfavorable Hodgkin's Interim results showed high CR rates and almost 100% PFS, OS at 12 months May 01, 2020
COVID-19 Mortality Spikes in Patients With Lung, Blood Cancers Those with metastatic disease also at special risk for poor outcomes Apr 28, 2020
DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
Immunotherapy Super-Responder: What Is Life, Not Exactly Cured? Lisa Geller's cancer has been gone nearly 4 years, but life has been far from normal Mar 02, 2020
Bringing Transplant to More Patients With AML Conditioning with radiolabeled antibody leads to successful transplantation in 84% of older patients Feb 25, 2020
New CAR-T Makes Case for Aggressive Lymphomas Largest trial to date shows 73% ORR, 53% CR, potential for outpatient treatment Feb 25, 2020
Stem-Cell Transplant Trial Ends in a Draw Similar PFS with haploidentical bone marrow, double unrelated umbilical cord blood Feb 24, 2020
Preemptive Anti-IL-6 May Cut Severe CRS With CAR-T Tx Targeting patients with high tumor burden reduced severe CRS by 50% Feb 22, 2020
Myeloablative Therapy Prevails in AML Transplant Study Better survival, fewer relapses compared with reduced-intensity conditioning Feb 21, 2020
Better Quality CR With One AML Therapy vs Another? Longer survival after CR/CRi with CPX-351 than with 7+3 in patients with AML-MRC Feb 21, 2020
Gains in Stem Cell Transplant Mortality Over Last 25 Years But outcomes still "far from perfect" Jan 20, 2020
What Is Causing This Woman's Swollen Chin? A long and challenging diagnostic path with twists and turns Jan 20, 2020
Higher Risk of Shingles Seen in Patients With Certain Cancers Vaccine development may help with prevention of herpes zoster in this population Dec 31, 2019
'Dark Waters': Behind-the-Scenes With Attorney Who Took on DuPont Chemical in Teflon was "completely unregulated" when Robert Bilott went after corporate giant Dec 19, 2019
Denosumab Use in Myeloma Soars for No Obvious Reason More expensive than competitor without being better, so why does it now have nearly half the market? Dec 12, 2019
Survival Bump With Oral AML Maintenance Ten-month OS gain, doubling of RFS with oral azacitidine in transplant-ineligible patients Dec 10, 2019
'Off-the-Shelf' Therapy Active After CAR T-Cell Failure Bispecific antibody mosunetuzumab targets CD3, CD20; needs no ex vivo T-cell processing Dec 07, 2019
Study Bolsters Case for Novel Xarelto Formulation for Kids Pharmacokinetic data indicate appropriate dosing schemes across wide range of weight categories Dec 07, 2019
IGHV-Unmutated CLL: Gene Signature May Predict Outcomes After First-Line FCR Prognostic tool may predict who is likely to achieve a relatively long remission Oct 15, 2019
FCR Still an Option in IGHV-Unmutated CLL? Gene signature identifies lower-risk group with greater chemoimmunotherapy benefit Oct 08, 2019
Ibrutinib's Cardiotoxicity Comes Into Focus Study identifies new cardiac events linked to so-called targeted therapy Sep 25, 2019
Red Cell Distribution Width Strongly Predicts Hip Fracture Simple way to identify at-risk patients Sep 24, 2019
Could Mom's Anemia Hurt Baby's Brain? Association study suggests an increased risk, though still quite small Sep 18, 2019
Good News, Bad News for CRISPR Gene Editing for HIV Cure "Bigger story for the gene-editing field than the HIV field" Sep 11, 2019
Serum Immune Markers May Predict Conversion From MGUS to Myeloma Results could support annual blood tests and risk assessment for those with MGUS and its subtype, light-chain MGUS Jul 19, 2019
TAVR Access Closure Devices Not Equal, Study Shows Separate study suggests bleed monitoring device could help May 23, 2019
Enoxaparin May Be Underdosed for CRC Surgery Patients Standard dose yielded low anticoagulation levels in 68% but no increase in venous thromboembolism May 23, 2019
Rheumatologist's Primer on Checkpoint Inhibitors Specialist reviews the landscape of cancer drugs' autoimmune side effects Apr 09, 2019
Bone Marrow Transplant for Autoimmune Disease: Ready for Prime Time? Everything you know about BMT is probably wrong, says hematologist Apr 08, 2019
Durable Responses With Keytruda in Later-Line SCLC Plus umbralisib in marginal zone lymphoma and a next-generation TRK-targeted agent Apr 04, 2019
Overall Survival Data in for Gilteritinib as AML Salvage Tx FLT3 Inhibitor tops chemotherapy in randomized trial Apr 01, 2019
Transplant No Help in Hypodiploid ALL Similar 5-year outcomes with or without HSCT, regardless of MRD status Mar 29, 2019
Are Patients Better Off With Image-Guided Bone Marrow Biopsy? Prospect of sedation has some going to interventional radiology Mar 29, 2019