Tranexamic Acid May Hurt Head Trauma Survival for One Key Group Cheap antifibrinolytic given en route to hospital safe overall in registry Dec 07, 2020
Fixed-Duration Ibrutinib-Venetoclax Promising in First-Line CLL DFS at 1 year reaches 95% in patients with undetectable MRD Dec 06, 2020
CRISPR-Based Tx Offers Hope in Tough-to-Treat Blood Disorders Success with investigational use of gene editing in sickle cell disease, beta-thalassemia Dec 06, 2020
Blood Cancers and COVID-19: 'A Medically Vulnerable' Group Patients with hematologic malignancies and SARS-CoV-2 face higher risks for infection, death Dec 06, 2020
JAK Inhibitor Wins in Second-Line Chronic GVHD Twice as many patients achieved a response at week 24 Dec 05, 2020
Sickle Cell Disease Tied to Worse COVID-19 Outcomes Black patients seem to be at higher risk for certain COVID-19 complications, death Dec 05, 2020
Three-Drug Regimen Reduces Myeloma Treatment Burden Efficacy maintained with addition of SQ daratumumab to pomalidomide, dexamethasone Dec 04, 2020
Bone Marrow Improves Healing With ACL Grafts MRI confirms better outcomes than with allograft alone in randomized study Dec 04, 2020
Newborns Getting Preoperative Blood Transfusions Have More Complications Data favor restrictive transfusion strategy Oct 22, 2020
CDK4/6 Inhibitor in SCLC Cuts Chemo-Induced Myelosuppression Reduced severe neutropenia and less need for supportive care with trilaciclib Oct 20, 2020
COVID Heart Autopsies Point More to Clot Damage Than Myocarditis Results bolster case for anticoagulation in hospitalized patients Oct 15, 2020
More Evidence Points to Role of Blood Type in COVID-19 Two studies find ties to infection susceptibility, severity, but with caveats Oct 14, 2020
Raising the Bar for Myelofibrosis Therapy Development Rational combinations, new targets, and a first-ever phase III trial with a survival endpoint Sep 14, 2020
New Anemia Linked to Crohnβs Disease but Not Ulcerative Colitis Risk Anemia seen as promising surrogate marker for preclinical CD, especially in men Sep 11, 2020
Severe Nosebleeds More Common With Hypertension Korean study supports link between hypertension and epistaxis Sep 10, 2020
REALITY Check: Stricter RBC Transfusion Safe for Anemic MI Patients Restrictive strategy makes sense for clinical outcomes, costs Sep 01, 2020
FDA OKs Anti-BCMA Drug for Multiple Myeloma Accelerated approval for belantamab mafodotin after four other therapies Aug 06, 2020
Skin Rashes a Clue to COVID-19 Vascular Disease Certain skin manifestations tied to coagulopathy in the sickest patients Aug 05, 2020
COVID-19 More Deadly Than Cancer Itself? Highlights from the AACR conference on COVID-19 and cancer Jul 24, 2020
The Serious Conversation: Delivering Bad News by Telemedicine As office visits move online, clinicians discuss breaking life-changing diagnoses virtually Jul 13, 2020
HIV: Don't Quit on Hope, Says 'London Patient' IAC roundtable addresses prospects for cure, now proven to be possible Jul 06, 2020
Cancer Immunotherapy Tied to Severe COVID-19 Outcomes Nearly threefold increased risk of hospitalization, severe respiratory illness Jun 25, 2020
Worse Blood Cancer Outcomes in Hispanics Diagnosis at earlier age, worse survival, especially for those on U.S.-Mexico border Jun 24, 2020
Combination Ups Survival in Older AML Patients Frontline venetoclax plus azacitidine adds 5 months to median OS versus azacitidine alone Jun 17, 2020
Biologic Effective in Light Chain Amyloidosis Anti-CD38 therapy added to conventional regimen boosts PFS in trial Jun 16, 2020
Keytruda Tops Adcetris in Head-to-Head Hodgkin's Trial Checkpoint inhibitor improved PFS in refractory and transplant-ineligible cases Jun 15, 2020
New Standard for Relapsed/Refractory Multiple Myeloma? Triplet regimen significantly extended median PFS versus doublet in IKEMA study Jun 15, 2020
High Marks for CAR T Cells in R/R Myeloma Response rates of 70-100% with BCMA-targeted products for heavily treated disease Jun 03, 2020
Early Palliation: Boon for AML Patients on Intensive Chemo Intervention led to marked improvements in QoL, mental distress, end-of-life care Jun 02, 2020
VRd Still Reigns in Newly Diagnosed Myeloma KRd fails to prove superiority in head-to-head trial Jun 01, 2020
CAR T-Cell Therapy Impresses in Indolent NHL Overall response rate exceeding 90% with axi-cel in relapsed/refractory setting May 31, 2020
Nivolumab-Based Tx Effective in Early, Unfavorable Hodgkin's Interim results showed high CR rates and almost 100% PFS, OS at 12 months May 01, 2020
COVID-19 Mortality Spikes in Patients With Lung, Blood Cancers Those with metastatic disease also at special risk for poor outcomes Apr 28, 2020
DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
Immunotherapy Super-Responder: What Is Life, Not Exactly Cured? Lisa Geller's cancer has been gone nearly 4 years, but life has been far from normal Mar 02, 2020
Bringing Transplant to More Patients With AML Conditioning with radiolabeled antibody leads to successful transplantation in 84% of older patients Feb 25, 2020
New CAR-T Makes Case for Aggressive Lymphomas Largest trial to date shows 73% ORR, 53% CR, potential for outpatient treatment Feb 25, 2020
Stem-Cell Transplant Trial Ends in a Draw Similar PFS with haploidentical bone marrow, double unrelated umbilical cord blood Feb 24, 2020
Preemptive Anti-IL-6 May Cut Severe CRS With CAR-T Tx Targeting patients with high tumor burden reduced severe CRS by 50% Feb 22, 2020
