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Generous Blood Transfusions Not Beneficial for Some With Burst Brain Aneurysms

SAHARA rounds out this year's notable trials on blood transfusions in critically ill patients

Dec 10, 2024
 A photo of a nurse holding a bag of red blood cells.
Benefits of Transplant for Pediatric Sickle Cell Disease Add Up a Decade Later

Better disease outcomes, measures of cognition, and quality-of-life vs standard care, study finds

Dec 10, 2024
ASH over a photo of San Diego Convention Center
Makers of Sickle Cell Disease Gene Therapy to Participate in Payment Model, CMS Says

Outcomes-based model designed to improve access to pricey treatments

Dec 04, 2024
 A computer rendering of sickle cells in the blood flow.
'Sex Party' COVID Czar Fired; Undiagnosed Iron Deficiency; Many Papers Partly Fake?

Health news and commentary gathered by 51˶ staff

Sep 25, 2024
Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.
Evidence Still Lacking for Iron Deficiency Screening, Supplementation in Pregnancy

USPSTF says new findings were consistent with those of previous review

Aug 20, 2024
A photo of a pregnant woman pouring iron supplements into her palm.
CDC Alerts on Dramatic Rise in Human Parvovirus B19

Pregnant people and those who are immunocompromised most at risk, agency warns

Aug 14, 2024
A computer rendering of parvovirus B19 particles.
Subcutaneous C5 Inhibitor Approved for PNH

Longer-acting crovalimab designed for more sustained effect and less treatment burden

Jun 24, 2024
FDA APPROVED crovalimab (Piasky) over a computer rendering of blood flowing inside a vessel.
Once-Rejected Drug Now FDA Approved for CKD-Related Anemia

Indication for HIF-PH inhibitor vadadustat limited to patients already on dialysis

Mar 28, 2024
FDA APPROVED vadadustat (Vafseo) over a photo of a woman receiving dialysis.
FDA Panel Endorses Imetelstat for MDS-Related Anemia

By 12-2 vote, members find improvement in transfusion independence outweighs risk

Mar 14, 2024
FDA ODAC imetelstat (Rytelo) over a close up photo of a person receiving a blood transfusion.
FDA Staff Cast Doubt on Novel Drug for MDS-Related Anemia

Agency asking its advisors if benefits outweigh risks for patients who fail on standard treatment

Mar 12, 2024
FDA ODAC imetelstat (Rytelo) over a close up photo of a person receiving a blood transfusion.
A Blenrep Comeback? Cancer Vaccine for Dogs; U.K. Snubs Enhertu

News, features, and commentary about cancer-related issues

Mar 07, 2024
Onco Break over a computer rendering of a cancer cell.
Gene Therapy for Sickle Cell Disease Likely Cost-Effective if Under $2 Million

Lifetime reduction in acute pain episodes should offset high upfront costs of the therapy

Jan 22, 2024
A computer rendering of red blood cells affected by sickle-cell disease
FDA Approves JAK Inhibitor That Addresses Anemia in Myelofibrosis

In a phase III trial, momelotinib reduced anemia, constitutional symptoms, and splenomegaly

Sep 18, 2023
FDA APPROVED momelotinib (Ojjaara) over a computer rendering of myelofibrosis cells.
New Recommendations Address Global Inequality in Sickle Cell Disease Care

Commission lays out strategies for progress by 2025 and beyond

Jul 13, 2023
A scanning electron microscope image of a sickle cell.
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