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News, opinions and meeting coverage in gastroenterology.
Consumer Group Urges Boxed Warning for PPIs
Citing research showing that withdrawal of proton pump inhibitors (PPIs) leads to severe rebound acid secretion -- potentially leaving patients permanently dependent on the drugs -- the consumer group Public Citizen has told the FDA that it should require black-box warnings with the drugs.
Aug 23, 2011
FDA Warns GERD Drugs May Deplete Magnesium
WASHINGTON -- Use of prescription or over-the-counter proton pump inhibitors (PPI) for a year or longer may lead to low levels of circulating magnesium, which may increase the risk of leg spasms, arrhythmias, and seizures, according to an FDA warning.
Mar 02, 2011