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Psoriasis

News, opinions and meeting coverage in dermatology.

A close up of a man鈥檚 hand with psoriatic arthritis over a bottle of Rinvoq (upadacitinib) tablets

JAK Inhibitor Promising in Psoriatic Arthritis

Oral agent noninferior to adalimumab in joint symptoms

The packaging of Taltz (ixekizumab) injection

Don't Stop Taltz in Psoriatic Arthritis

Significantly more patients relapsed, and more quickly, after withdrawal

A computer rendering of monoclonal antibodies

Monoclonal Antibody Highly Effective in Phase III Psoriasis Trial

Beats ustekinumab, but main side effect was oral candidiasis

ACR over a computer rendering of a human skeleton with the joints of the fingers highlighted in red

TYK2 Inhibition Promising in Psoriatic Arthritis

Phase II study found significant benefits for two doses of novel agent

EADV over a collage of venereology/dermatology icons

Gut Bacteria for Psoriasis; Long-Term Hair Growth; COVID and STDs

Selected presentations from the European Academy of Dermatology and Venereology virtual conference

EADV over a collage of venereology/dermatology icons

Nonsteroidal Topical, Nanodrug Active in Psoriasis

Selected presentations from the European Academy of Dermatology and Venereology meeting

A healthcare worker wearing white gloves holds a woman鈥檚 swollen hand

Targeting IL-23 Relieves Multiple Symptoms in PsA

Both enthesitis and dactylitis improved with guselkumab treatment in psoriatic arthritis

A dermatologist wearing blue gloves applies a cream to a patient鈥檚 elbow who has psoriasis

Psoriasis Cream Succeeds in Early Trial

PDE-4 inhibitor helped clear plaque psoriasis in 6 weeks

EULAR over a computer rendering of a human body with the major joints glowing red

Psoriatic Arthritis: Outcomes Similar for Cosentyx and Humira

Primary endpoint of superiority for secukinumab over adalimumab not met in a phase IIIb trial

EULAR over a computer rendering of a human body with the major joints glowing red

EULAR 2020: What to Expect

Cancelled due to pandemic but extensive menu of virtual learning planned

A computer rendering of an antibody

Biologics Don't Increase Melanoma Risk... Probably

Meta-analysis offers some reassurance, but leaves room for doubt

The packaging and prefilled syringe of Tremfya

Guselkumab a Hit in Phase III for PsA

Primary endpoints met in two large trials in psoriatic arthritis for IL-23 inhibitor

The packaging for Skyrizi

Psoriasis IL-23 Biologic Maintains Efficacy in 2-Year Trial

Phase III trial looked at risankizumab (Skyrizi)

A photo of a person鈥檚 hands with prurigo nodularis

IL-31 Drug Succeeds for Prurigo Nodularis

Less itching and twice as many lesions resolved with investigational agent

A computer rendering of infliximab

Confirmed: TNF Inhibitors Don't Raise Cancer Risk

Reassurance from national study in Denmark

ACR over a photo of Georgia World Congress Center in Atlanta, Georgia.

Reassurance on Live-Virus Shingles Vax With Anti-TNFs

Randomized trial indicates fears of infection unfounded

Psoriasis Model: Ketogenic Diets' Effects Not Equal

Some fats affect the skin more than others, preclinical study suggests

A pie chart showing the ketogenic diet, 70-80% fat, 20-25% protein, 5-10% carbohydrates

Got Psoriasis? Maybe Best to Avoid Certain Keto Diets

Animal study suggests the two don't always play together nicely

Fall Derm over a photo of the Wynn, Las Vegas, NV

JAK Inhibitors Emerging as Oral Option for Psoriasis

But older oral therapies remain key therapeutic players for many patients

Fall Derm over a photo of the Wynn, Las Vegas, NV

Chronic Itch: New Therapy, Complexities

"End of the antihistamine era" as new strategies target neural mechanisms

A computer rendering of brain neuron and amyloid plaques

Can Anti-TNF Drugs Reduce Alzheimer's Risk?

Analysis of 56 million patients hints at possible connections

A photo of Kim Kardashian

Kim Kardashian West鈥檚 Mystery Illness Revealed

Rheumatologists may have already guessed

EULAR over a photo of IFEMA Feria de Madrid.

IL-17a Drug Rescues Many Refractory Psoriatic Arthritis Cases

Disease abated in half of patients receiving secukinumab after failing other biologics

EULAR over a photo of IFEMA Feria de Madrid.

No Cancer Risk Found With TNF Inhibitors in Psoriatic Arthritis

Expected cancer cases similar to those in general populace, study shows

Cosentyx box and injection pens.

Cosentyx Safety Confirmed Through 5 Years

Safety profile favorable in psoriasis, psoriatic arthritis, and ankylosing spondylitis

A young woman with vitiligo.

Vitiligo, Alopecia Merely Cosmetic? Think Again

Studies show links with depression, quality of life -- and early death

Sheraton Grand hotel in Chicago with ACR-SOTA text overlaid.

Bone Marrow Transplant for Autoimmune Disease: Ready for Prime Time?

Everything you know about BMT is probably wrong, says hematologist

When Not to Use Biologics for Psoriasis

Comorbidities, special populations, idiosyncrasies influence decisions

IBD Rates Low in Patients on Cosentyx

Analysis of data from 21 clinical trials in psoriasis, psoriatic arthritis, and ankylosing spondylitis

Two-Drug Regimen Fails to Stem Psoriasis Relapse

Study looks at costimulatory blockade with abatacept after stopping ustekinumab

Skin Lesions Linked With Anti-TNF in IBD

Most paradoxical psoriasiform eruptions were managed locally

Skin-Stripping Test Promising for Inflammatory Skin Diseases

Protein analysis may help differentiate between eczema, psoriasis

PASDAS: Targeting Multiple Aspects of PsA

Secukinumab showed efficacy for the various domains of psoriatic arthritis

In Psoriatic Arthritis, Doubling Down on IL-17

Bimekizumab targets both IL-17A and F; "astonishing" results in psoriatic arthritis

Psoriasis Response Falls as Comorbidities Rise

Comorbid conditions reported in two-thirds of patients

Minimal Disease Activity: The Goal in PsA

Validity confirmed in large population of patients

Enthesitis in PsA: A New Focus of Treatment?

Targeting IL-23 with ustekinumab cleared enthesitis in three-quarters of patients

Can Diet Help in Psoriasis?

Foundation's recommendations center on weight loss

4-Year Data in PsA Reassuring for Apremilast

Benefits persist for joints and skin

Make the Diagnosis: Itchy Fingers from IV Therapy?

Case Findings: A 48-year-old woman who was receiving IV immunoglobulin therapy complained to her doctor that over the past few weeks small vesicles had formed along the sides of her fingers. Some had ruptured and become scaly papules. Her fingers were extremely pruritic, and she said it was "driving her crazy." Can you diagnose the patient?

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