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The American Heart Association (AHA) unveiled its for estimating heart attack, stroke, and heart failure risk over 10 or 30 years for people ages 30 and older. The tool removes race from the calculation and would supplant the Pooled Cohort Equations.

Whistleblowers point to scientific misconduct and an early uptick in mortality in studies of . (Science)

Serum lipoprotein(a) concentrations plummeted with administration of the short interfering RNA therapy in a dose-finding trial. (JAMA)

A appeared safe and feasible based on a high-risk patient cohort with severe symptomatic aortic valve stenosis. (The Lancet)

For people with atrial fibrillation (Afib), the cut bleeds compared with rivaroxaban (Xarelto) in the AZALEA-TIMI 71 study highlighted by the AHA.

People with sleep apnea tend to be at higher risk of . (Journal of the American Heart Association)

Two to 4 weeks of cessation of combined hormonal contraceptives was enough for the . (Blood)

For CPR, was strongly associated with improved return of spontaneous circulation, survival, and survival with favorable neurological outcome. (Circulation)

ECG changes over time are a marker for sudden cardiac arrest, suggesting value in for better identification of high-risk individuals in the future. (European Heart Journal)

A decline in eGFR in the first month after initiation of the SGLT2 inhibitor dapagliflozin (Farxiga) in patients with heart failure and mildly reduced or preserved ejection fraction. (JAMA Cardiology)

In the DAPA-MI trial, dapagliflozin had no clinical benefit on select who did not have chronic heart failure at baseline. (NEJM Evidence)

Medtronic announced that it reduced thanks to artificial intelligence algorithm enhancements.

Researchers established parameters indicating normal and disease-specific changes on . (Journal of the American College of Cardiology)

There are persistently high 30- and 60-day readmissions for . (JACC: Heart Failure)

The Institute for Clinical and Economic Review handed sotatercept a health-benefit price benchmark of , or the maximum it should cost as a treatment for pulmonary arterial hypertension.

was linked to cardiovascular and psychiatric conditions for the child in subsequent adulthood. (Nature Communications)

Does treatment of benign prostatic hyperplasia with confer excess cardiovascular events? (JAMA Network Open)

Mount Sinai announced that its researchers are sending bioengineered so that the effects of microgravity can be studied.

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