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Farxiga OK'd for All EF; Older Donor Hearts; Cardiologist Arrested for Deaths

— Recent developments of interest in cardiovascular medicine

MedpageToday
Cardio Break over a computer rendering of a heart.

FDA gave expanded approval to the SGLT-2 inhibitor dapagliflozin (Farxiga) for preventing cardiovascular death, heart failure hospitalization, and urgent heart failure visits in all patients with heart failure , AstraZeneca announced.

Based on the EMPEROR trials, empagliflozin (Jardiance) consistently reduced heart failure events across the . (Journal of the American College of Cardiology)

In a large Spanish study of the prognostic values of clinic and 24-hour ambulatory blood pressure assessment, emerged as having the strongest ties to all-cause mortality and cardiovascular death over a decade. (The Lancet)

People who spend tend to have a greater risk of new-onset hypertension over the next 12 years. (European Heart Journal Digital Health)

In the Million Veteran Program, adding slightly improved risk stratification for atherosclerotic cardiovascular disease. (JAMA Cardiology)

Priced at $250 a test, for Lynch syndrome, hereditary breast and ovarian cancer, and familial hypercholesterolemia would be cost-effective in adults under 40. (Annals of Internal Medicine)

The American Heart Association highlighted the cardiovascular research disparities across and urged better risk estimation for these populations. (Circulation)

Elevated systemic levels of cytokines and other immune features are a signature of patients who developed . (Science Immunology)

Outside COVID-19, had no impact on all-cause mortality in critically ill people with infectious diseases, a meta-analysis found. (International Journal of Cardiology)

Endovascular therapy for stroke was supported by a meta-analysis of seven studies. (JAMA Network Open)

Survival was not affected for transplant recipients in their 70s who received in an observational study with implications for expanding the organ donor pool. (Annals of Thoracic Surgery)

The of vein of Galen malformation in the brain occurred at 34 weeks and 2 days gestational age. The baby was born requiring no heart failure medication and no further surgical repair of the malformation. (Stroke)

A nationwide survey found gaps in among cancer patients. (European Journal of Preventive Cardiology)

The decongestive response to acetazolamide was magnified in heart failure patients with in a subanalysis of the ADVOR trial. (European Heart Journal)

A higher , indicating greater arterial stiffness, predicted postoperative atrial fibrillation after cardiac surgery. (European Heart Journal Open)

A diagnosis of Brugada syndrome was associated with among one in six people within 5 years. (EP Europace)

Scientists looked at how affect the developing cardiovascular system in a chicken egg model. (FASEB Journal)

A Berlin cardiologist was arrested after it was determined that two ICU patients who died under his care had received . (Reuters)

  • author['full_name']

    Nicole Lou is a reporter for 51˶, where she covers cardiology news and other developments in medicine.