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Cardiology

News, opinions and meeting coverage in cardiology.

HFSA: Controversy Highlighted at Upcoming Meeting

BOSTON -- Much progress has been made in managing heart failure, but there are still some areas of controversy that will be highlighted at the upcoming meeting of the Heart Failure Society of America here.

EASD: Gestational Diabetes Guidelines Controversial

LISBON -- International guidelines on screening for gestational diabetes that will likely raise the prevalence of the condition have sparked questions over appropriate diagnostic tools and cost efficacy, researchers said here.

FDA Warns Against High-Dose Citalopram

Citing increased risk of cardiac arrhythmias and a lack of therapeutic benefit associated with high doses of the SSRI citalopram hydrobromide (Celexa), the FDA has reduced the recommended maximum to 40 mg/day.

Level of Diastolic Function Predicts Death

The presence of moderate or severe diastolic dysfunction in patients with preserved systolic function independently predicted mortality, a retrospective study determined.

Cordis to Stop Making Cypher, Nevo Stents

Cypher, the first drug-eluting coronary stent to receive FDA approval, will be discontinued at the end of the year, according to manufacturer Cordis.

Cancer Risk Forces Actos Off French, German Markets

Drug regulators in Germany and France have ordered doctors to stop prescribing the type 2 diabetes drug pioglitazone (Actos), following a French study suggesting a heightened risk of bladder cancer.

FDA Warns Against Use of High-Dose Simvastatin

The highest approved dose of simvastatin -- 80 mg -- should be used only in those patients who have already been taking it for at least 12 months without signs of myopathy, the FDA announced Wednesday.

Lab Notes: Red Wine Before Radiation and Red Clover for Hair Loss

Red is the color of the day, as components of red wine and red clover lead this week's Lab Notes, but the blues get their turn in the spotlight, too, as depressed people outshine cheerier folks in some elements of decision making.

Diet, Exercise Sufficient to Reduce Triglycerides

While cholesterol control is often balanced between statins and lifestyle changes, reducing triglycerides can usually be accomplished with diet and lifestyle changes alone, according to a new scientific statement from the American Heart Association.

New ARB Cleared for Hypertension Treatment

The FDA has approved azilsartan medoxomil (Edarbi), an oral angiotensin II receptor blocker (ARB) for hypertension, expanding the ranks of ARBs now available to U.S. patients.

Use Dabigatran Within 30 Days of Opening

Unbeknownst to many physicians, bottles of the new oral anticoagulant dabigatran (Pradaxa) must be used within 30 days of opening, according to information from the manufacturer.

Cardiologist Who Revealed Echo Errors Out of a Job

MILWAUKEE -- A cardiologist whose research at a national medical meeting revealed that other doctors at her hospital were misreading a substantial number of diagnostic echocardiograms has been fired by that hospital, the Journal Sentinel and 51成人动漫 have learned.

Abnormal Liver Enzymes No Reason to Avoid Statins

Statins are not only safe and effective for patients with liver enzyme abnormalities but also appear to improve their liver function, researchers found.

AHA: One or Two Drinks May Not Hurt Bypass Patients

CHICAGO -- Having an alcoholic drink does not appear to cause problems for patients following coronary artery bypass graft surgery -- but doctors warn that these patients cannot have more than one or two drinks a day.

AHA: Rivaroxaban Scores Win While Omega-3 Flops

CHICAGO -- Good news and not so good news about investigational treatments for atrial fibrillation are featured in this exclusive InFocus video report from the American Heart Association meeting.

FDA Panel Looks at Trials of Devices to Treat Depression

GAITHERSBURG, Md. -- An FDA advisory panel met Friday to discuss how to analyze trials designed to test devices used to treat depression, but didn't offer the FDA any clear-cut guidance.

TORPEDO Trial: Mohsen Sharifi, MD

WASHINGTON -- In this exclusive press conference, Dr. Sharifi presents a prospective randomized trial of percutaneous endovenous intervention compared to anticoagulation alone in patients with deep venous thrombosis.

COMPARE Trial: Peter C. Smits, MD, PhD

WASHINGTON -- In this exclusive press conference, Dr. Smits presents two-year results from a prospective randomized trial of everolimus-eluting stents compared to paclitaxel-eluting stents in patients with coronary artery disease.

Ornish, Pritikin Cleared for Medicare Payment

Medicare will pay for intensive diet and exercise programs developed under the Ornish and Pritikin brands for reducing cardiovascular event risk, the Centers for Medicare and Medicaid Services announced.

Artificial Heart Now Sold Online

The maker of the only FDA-approved temporary total artificial heart has opened an online store to take orders for the device and its accessories.

Take Rosiglitazone Off the Market, Says FDA Staff

WASHINGTON -- Rosiglitazone (Avandia) should be pulled from the market because of the "serious" cardiovascular risk the diabetes drug poses, which exceeds that of competitor pioglitazone (Actos), FDA staff reviewers again recommended.

Common Antibiotic Linked to Elevated Potassium

Among older individuals, the commonly used antibiotic trimethoprim-sulfamethoxazole (TMP-SMX) is associated with the development of hyperkalemia requiring hospitalization, researchers found.

ASE: Routine 3D Echo Use Debated

SAN DIEGO -- Three-dimensional echocardiography has won many supporters but not everyone is convinced that it's ready for widespread clinical use.

Giving tPA Late: Risk May Outweigh Benefit

Although beneficial within 4.5 hours of stroke onset, administering recombinant tissue plasminogen activator (tPA) beyond that window appears to increase the risk of dying, a pooled analysis of eight clinical trials showed.

Heart, Not Ear, Main Source of Dizziness in Elderly

Heart disease, not inner ear problems, appears to be the most common cause of dizziness in elderly patients seen in primary care offices, researchers say.

ASH: Hypertension Plus Tachycardia Equals High Risk

NEW YORK -- An elevated resting heart rate is associated with an increased risk of cardiac events in high-risk hypertension, according to a secondary analysis of a large randomized trial.

In Pregnancy, DVT Mostly Occurs in Left Leg

Pregnant women are more likely to have deep vein thrombosis in their left leg, researchers have found.

ACC: Triglycerides Decreased with Rosuvastatin Therapy

ATLANTA -- In a study that specifically scrutinized the effects of statin therapy on triglycerides, researchers said that rosuvastatin (Crestor) significantly reduced the blood lipid that has been linked to coronary artery disease better than placebo.

ACC: Clopidogrel Black Box Likely to Have Immediate Clinical Impact

ATLANTA -- The FDA's decision to add a black box warning to the label of clopidogrel (Plavix) came without warning to doctors attending the American College of Cardiology meeting here. But getting the word out to more than 13,000 cardiologists gathered in this city not an easy task.

ACC: FDA Announces Review of ACCORD Data

ATLANTA -- The FDA said it will conduct a full review of findings from a study which concluded that neither aggressive lipid-lowering therapy nor tight blood pressure control reduced cardiovascular events in persons with diabetes.

ASCO GU: BP Reveals Hit or Miss for Targeted Tx

SAN FRANCISCO -- Early response to preoperative targeted therapy for metastatic renal cell carcinoma may indicate efficacy, while treatment-induced hypertension may be another marker after surgery, according to studies reported here.

Stinky Diabetes Drug May Result in Poor Adherence

An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

Ending Statins May Not End Associated Muscle Pains

Patients experiencing muscle pain and weakness as a result of statin treatment may continue to suffer symptoms long after stopping the drugs, French researchers reported.

Canadian Politician Comes to U.S. for Heart Surgery

The top politician in Canada's easternmost province has set off fireworks by deciding to go to the U.S. for heart surgery.

Hidden Dangers of Herbal Meds Reviewed

Herbal medicines are not always the harmless nostrums that many patients and even some physicians think, but may actually contribute to cardiovascular morbidity and mortality, researchers warned.

Abnormal Lipid Levels Common in Teens

One in five American adolescents has unhealthy cholesterol and triglyceride levels, suggesting that targeted screening of youths would be a good idea, CDC researchers said.

AHA: FDA Drops Clopidogrel Bomb at AHA

ORLANDO -- The FDA has issued a public health advisory warning patients and physicians that concommitant use of clopidogrel (Plavix) and omeprazole (Prilosec and Prilosec OTC) blunts the antiplatelet effect of clopidogrel, so the combination should be avoided.

CT Safety Warnings Follow Radiation Overdose Accident

Reports of stroke patients who were accidentally exposed to eight times the normal radiation dose during diagnostic CT scans at Cedars-Sinai Medical Center in Los Angeles are prompting safety warnings and soul searching in radiology.

FDA Finds Oral Insulin Spray Safe for IND Use

The FDA approved Oral-lyn, an insulin spray treatment for type I and type II diabetes, for its Investigational New Drug program.

Kidney Disease Raises Risk of Hypoglycemia

WHEELING, W.Va. -- Dangerous hypoglycemic episodes are a significant risk for patients with chronic kidney disease, whether they have diabetes or not, researchers said.

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